| Gene Symbol | Avpr1a |
|---|---|
| Entrez Gene | 25107 |
| Alt Symbol | AVPR, V1a, V1aR |
| Species | Rat |
| Gene Type | protein-coding |
| Description | arginine vasopressin receptor 1A |
| Other Description | antidiuretic hormone receptor 1a|arginine vasopressin receptor V1a|vascular/hepatic-type arginine vasopressin receptor|vasopressin V1a receptor |
| Swissprots | Q62874 Q5M8D1 Q9QW18 P30560 |
| Accessions | AAC52507 BAA20859 EDM16542 P30560 BC088095 AAH88095 Z11690 CAA77748 NM_053019 NP_444178 |
| Function | Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Involved in social memory formation. {ECO:0000269|PubMed:12887422}. |
| Subcellular Location | Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Located in cytoplasmic vesicles dispersed throughout the cell cytoplasm and to the plasma membrane. |
| Tissue Specificity | Localized within gonadotropes of the anterior pituitary of the brain. Broadly distributed throughout the cerebral cortex. {ECO:0000269|PubMed:12399435, ECO:0000269|PubMed:9105680}. |
| Top Pathways | Calcium signaling pathway, Vascular smooth muscle contraction, Neuroactive ligand-receptor interaction |