| Gene Symbol |
Avpr1a
|
| Entrez Gene |
25107
|
| Alt Symbol |
AVPR, V1a, V1aR
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
arginine vasopressin receptor 1A
|
| Other Description |
antidiuretic hormone receptor 1a|arginine vasopressin receptor V1a|vascular/hepatic-type arginine vasopressin receptor|vasopressin V1a receptor
|
| Swissprots |
Q62874 Q5M8D1 Q9QW18 P30560
|
| Accessions |
AAC52507 BAA20859 EDM16542 P30560 BC088095 AAH88095 Z11690 CAA77748 NM_053019 NP_444178
|
| Function |
Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Involved in social memory formation. {ECO:0000269|PubMed:12887422}.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Located in cytoplasmic vesicles dispersed throughout the cell cytoplasm and to the plasma membrane.
|
| Tissue Specificity |
Localized within gonadotropes of the anterior pituitary of the brain. Broadly distributed throughout the cerebral cortex. {ECO:0000269|PubMed:12399435, ECO:0000269|PubMed:9105680}.
|
| Top Pathways |
Calcium signaling pathway, Vascular smooth muscle contraction, Neuroactive ligand-receptor interaction
|