Gene Symbol | VWCE |
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Entrez Gene | 220001 |
Alt Symbol | URG11, VWC1 |
Species | Human |
Gene Type | protein-coding |
Description | von Willebrand factor C and EGF domains |
Other Description | HBV X protein up-regulated gene 11 protein|HBxAg up-regulated gene 11 protein|von Willebrand factor C and EGF domain-containing protein |
Swissprots | A5PKV0 Q96DN2 Q7Z7L6 Q86WK8 |
Accessions | EAW73929 EAW73930 EAW73931 EAW73932 Q96DN2 AA328361 AK056571 BAB71219 AK299583 BAG61518 AK302241 BAG63593 AY205235 AAO47606 BC042143 BC052564 BC077719 BC142624 AAI42625 DB126089 XM_006718460 XP_006718523 XM_006718462 XP_006718525 XM_011544815 XP_011543117 XM_011544816 XP_011543118 XM_011544817 XP_011543119 XM_011544818 XP_011543120 XM_011544819 XP_011543121 XM_011544820 XP_011543122 XR_949821 XR_949822 XR_949823 XR_949825 NM_152718 NP_689931 |
Function | May be a regulatory element in the beta-catenin signaling pathway and a target for chemoprevention of hapatocellular carcinoma. {ECO:0000269|PubMed:16496348}. |
Subcellular Location | Secreted {ECO:0000305}. Note=According to PubMed:16496348 is localized in the cytoplasm. {ECO:0000269|PubMed:16496348}. |
Tissue Specificity | Expressed in liver. {ECO:0000269|PubMed:16496348}. |
VWC1 CRISPR/Cas9 KO Plasmid (h) - sc-415100 from Santa Cruz Biotechnology
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VWC1 HDR Plasmid (h) - sc-415100-HDR from Santa Cruz Biotechnology
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VWC1 Double Nickase Plasmid (h) - sc-415100-NIC from Santa Cruz Biotechnology
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VWC1 Double Nickase Plasmid (h2) - sc-415100-NIC-2 from Santa Cruz Biotechnology
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VWC1 CRISPR Activation Plasmid (h) - sc-415100-ACT from Santa Cruz Biotechnology
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VWC1 CRISPR Activation Plasmid (h2) - sc-415100-ACT-2 from Santa Cruz Biotechnology
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VWC1 Lentiviral Activation Particles (h) - sc-415100-LAC from Santa Cruz Biotechnology
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VWC1 Lentiviral Activation Particles (h2) - sc-415100-LAC-2 from Santa Cruz Biotechnology
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VWC1 siRNA (h) - sc-96303 from Santa Cruz Biotechnology
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VWC1 shRNA Plasmid (h) - sc-96303-SH from Santa Cruz Biotechnology
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VWC1 shRNA (h) Lentiviral Particles - sc-96303-V from Santa Cruz Biotechnology
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VWCE RNAi - H00220001-R01 from Novus Biologicals
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MISSION® esiRNA - EHU158441 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22769 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22769 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03560 from Sigma-Aldrich
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VWCE siRNA (Human) - CRJ6447 from Cohesion Biosciences
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VWCE - MBS8219438 from MyBioSource
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shRNA set against Human Vwce (NM_152718.2) - SHH445492 from Creative biogene
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Human VWCE siRNA - orb276948 from Biorbyt
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VWCE shRNA Plasmid (Human) - CHJ6447 from Cohesion Biosciences
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VWCE miRNA 3'UTR clone - MiUTR1H-11179 from Creative biogene
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