Hpse2

Gene Symbol Hpse2
Entrez Gene 545291
Alt Symbol Gm968, Hpa2
Species Mouse
Gene Type protein-coding
Description heparanase 2
Other Description inactive heparanase-2
Swissprots B2RY83
Accessions B2RY83 AK034730 BC158131 AAI58132 BC158133 AAI58134 BC158136 AAI58137 CN669340 XM_006527214 XP_006527277 XM_011247292 XP_011245594 XM_011247293 XP_011245595 XM_011247294 XP_011245596 XM_011247295 XP_011245597 XM_011247296 XP_011245598 NM_001081257 NP_001074726
Function Binds heparin and heparan sulfate with high affinity, but lacks heparanase activity. Inhibits HPSE, possibly by competing for its substrates (in vitro) (By similarity). {ECO:0000250}.
Subcellular Location Secreted, extracellular space, extracellular matrix {ECO:0000250}.
Top Pathways Proteoglycans in cancer, Glycosaminoglycan degradation

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