Gene Symbol |
Hpse2
|
Entrez Gene |
545291
|
Alt Symbol |
Gm968, Hpa2
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
heparanase 2
|
Other Description |
inactive heparanase-2
|
Swissprots |
B2RY83
|
Accessions |
B2RY83 AK034730 BC158131 AAI58132 BC158133 AAI58134 BC158136 AAI58137 CN669340 XM_006527214 XP_006527277 XM_011247292 XP_011245594 XM_011247293 XP_011245595 XM_011247294 XP_011245596 XM_011247295 XP_011245597 XM_011247296 XP_011245598 NM_001081257 NP_001074726
|
Function |
Binds heparin and heparan sulfate with high affinity, but lacks heparanase activity. Inhibits HPSE, possibly by competing for its substrates (in vitro) (By similarity). {ECO:0000250}.
|
Subcellular Location |
Secreted, extracellular space, extracellular matrix {ECO:0000250}.
|
Top Pathways |
Proteoglycans in cancer, Glycosaminoglycan degradation
|