Gene Symbol | Nlrc5 |
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Entrez Gene | 434341 |
Alt Symbol | AI451557, AK220210, NOD27 |
Species | Mouse |
Gene Type | protein-coding |
Description | NLR family, CARD domain containing 5 |
Other Description | protein NLRC5 |
Swissprots | C3VPR6 Q571H9 |
Accessions | C3VPR6 EDL11134 AK155962 BAE33524 AK220210 BAD90135 BC150954 FJ889356 ACP40992 XM_006531162 XP_006531225 XM_006531163 XP_006531226 XM_006531164 XP_006531227 XM_006531165 XP_006531228 XM_006531166 XP_006531229 XM_011248428 XP_011246730 NM_001033207 NP_001028379 |
Function | Probable regulator of the NF-kappa-B and type I interferon signaling pathways. May also regulate the type II interferon signaling pathway. Plays a role in homeostatic control of innate immunity and in antiviral defense mechanisms. {ECO:0000269|PubMed:20434986}. |
Subcellular Location | Cytoplasm {ECO:0000250}. |
Tissue Specificity | Expressed in spleen, thymus and lung. {ECO:0000269|PubMed:20434986}. |
Nlrc5 CRISPR/Cas9 KO Plasmid (m) - sc-436677 from Santa Cruz Biotechnology
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Nlrc5 HDR Plasmid (m) - sc-436677-HDR from Santa Cruz Biotechnology
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Nlrc5 Double Nickase Plasmid (m) - sc-436677-NIC from Santa Cruz Biotechnology
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Nlrc5 Double Nickase Plasmid (m2) - sc-436677-NIC-2 from Santa Cruz Biotechnology
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Nlrc5 CRISPR Activation Plasmid (m) - sc-436677-ACT from Santa Cruz Biotechnology
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Nlrc5 CRISPR Activation Plasmid (m2) - sc-436677-ACT-2 from Santa Cruz Biotechnology
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Nlrc5 Lentiviral Activation Particles (m) - sc-436677-LAC from Santa Cruz Biotechnology
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Nlrc5 Lentiviral Activation Particles (m2) - sc-436677-LAC-2 from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU169021 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN36503 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND36503 from Sigma-Aldrich
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NLRC5 siRNA (Mouse) - CRN5086 from Cohesion Biosciences
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shRNA set against Mouse NLRC5 (NM_001033207.3) - SHH352888 from Creative biogene
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Mouse NLRC5 siRNA - orb294561 from Biorbyt
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NLRC5 shRNA Plasmid (Mouse) - CHN5086 from Cohesion Biosciences
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