Gene Symbol | NPY1R |
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Entrez Gene | 4886 |
Alt Symbol | NPY1-R, NPYR |
Species | Human |
Gene Type | protein-coding |
Description | neuropeptide Y receptor Y1 |
Other Description | neuropeptide Y receptor type 1 |
Swissprots | B2R6H5 P25929 |
Accessions | CAA01787 CBH19834 EAX04841 P25929 A26481 CAA01819 AB209237 BAD92474 AK296624 BAG59231 AK298282 BAG60542 AK312578 BAG35472 AY548168 AAS55647 BC036657 AAH36657 BC071720 AAH71720 DA531980 DQ891265 ABM82191 DQ894453 ABM85379 L07614 L07615 AAA59947 M84755 AAA59920 M88461 AAA73215 XM_005263031 XP_005263088 XM_011532010 XP_011530312 NM_000909 NP_000900 |
Function | Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is NPY > [Pro-34] PYY, PYY and [Leu-31, Pro-34] NPY > NPY (2-36) > [Ile-31, Gln-34] PP and PYY (3-36) > PP > NPY free acid. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Top Pathways | cAMP signaling pathway, Neuroactive ligand-receptor interaction |
NPY1-R CRISPR/Cas9 KO Plasmid (h) - sc-416439 from Santa Cruz Biotechnology
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NPY1-R HDR Plasmid (h) - sc-416439-HDR from Santa Cruz Biotechnology
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NPY1-R Double Nickase Plasmid (h) - sc-416439-NIC from Santa Cruz Biotechnology
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NPY1-R Double Nickase Plasmid (h2) - sc-416439-NIC-2 from Santa Cruz Biotechnology
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NPY1-R CRISPR Activation Plasmid (h) - sc-416439-ACT from Santa Cruz Biotechnology
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NPY1-R CRISPR Activation Plasmid (h2) - sc-416439-ACT-2 from Santa Cruz Biotechnology
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NPY1-R Lentiviral Activation Particles (h) - sc-416439-LAC from Santa Cruz Biotechnology
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NPY1-R Lentiviral Activation Particles (h2) - sc-416439-LAC-2 from Santa Cruz Biotechnology
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NPY1-R siRNA (h) - sc-36097 from Santa Cruz Biotechnology
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NPY1-R shRNA Plasmid (h) - sc-36097-SH from Santa Cruz Biotechnology
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NPY1-R shRNA (h) Lentiviral Particles - sc-36097-V from Santa Cruz Biotechnology
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NPY1R RNAi - H00004886-R02 from Novus Biologicals
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MISSION® esiRNA - EHU125991 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15479 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15479 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09051 from Sigma-Aldrich
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NPY1R siRNA (Human) - CRH3247 from Cohesion Biosciences
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shRNA set against Human NPY1R (NM_000909.5) - SHH354548 from Creative biogene
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NPY1R shRNA Plasmid (Human) - CHH3247 from Cohesion Biosciences
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NPY1R miRNA 3'UTR clone - MiUTR3H-01539 from Creative biogene
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