Gene Symbol | OTX1 |
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Entrez Gene | 5013 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | orthodenticle homeobox 1 |
Other Description | homeobox protein OTX1|orthodenticle homolog 1 |
Swissprots | A6NHA2 P32242 B3KTJ4 Q53TG6 |
Accessions | AAY24357 BAA90421 EAW99966 EAW99967 EAW99968 P32242 AK095680 BAG53106 AK297308 BAG59774 BC007621 AAH07621 BM720707 BP310240 BU689444 DQ893301 ABM84227 DQ896509 ABM87508 NM_001199770 NP_001186699 NM_014562 NP_055377 NR_130153 |
Function | Probably plays a role in the development of the brain and the sense organs. Can bind to the BCD target sequence (BTS): 5'-TCTAATCCC-3'. |
Subcellular Location | Nucleus {ECO:0000305}. |
Tissue Specificity | Expressed in brain. Detected in the anterior part of the neural fetal retina (at protein level). {ECO:0000269|PubMed:19414065}. |
Top Pathways | Signaling pathways regulating pluripotency of stem cells |
OTX1 CRISPR/Cas9 KO Plasmid (h) - sc-416446 from Santa Cruz Biotechnology
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OTX1 HDR Plasmid (h) - sc-416446-HDR from Santa Cruz Biotechnology
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OTX1 Double Nickase Plasmid (h) - sc-416446-NIC from Santa Cruz Biotechnology
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OTX1 Double Nickase Plasmid (h2) - sc-416446-NIC-2 from Santa Cruz Biotechnology
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OTX1 CRISPR Activation Plasmid (h) - sc-416446-ACT from Santa Cruz Biotechnology
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OTX1 CRISPR Activation Plasmid (h2) - sc-416446-ACT-2 from Santa Cruz Biotechnology
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OTX1 Lentiviral Activation Particles (h) - sc-416446-LAC from Santa Cruz Biotechnology
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OTX1 Lentiviral Activation Particles (h2) - sc-416446-LAC-2 from Santa Cruz Biotechnology
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OTX1 siRNA (h) - sc-38739 from Santa Cruz Biotechnology
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OTX1 shRNA Plasmid (h) - sc-38739-SH from Santa Cruz Biotechnology
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OTX1 shRNA (h) Lentiviral Particles - sc-38739-V from Santa Cruz Biotechnology
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OTX1/2 siRNA (h) - sc-43985 from Santa Cruz Biotechnology
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OTX1/2 shRNA Plasmid (h) - sc-43985-SH from Santa Cruz Biotechnology
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OTX1/2 shRNA (h) Lentiviral Particles - sc-43985-V from Santa Cruz Biotechnology
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Otx1 RNAi - H00005013-R01V from Novus Biologicals
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Otx1 RNAi - H00005013-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN16204 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16204 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06934 from Sigma-Aldrich
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OTX1 siRNA (Human) - CRH3328 from Cohesion Biosciences
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shRNA set against Human OTX1 (NM_014562.3) - SHH369192 from Creative biogene
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Human OTX1 siRNA - orb263830 from Biorbyt
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OTX1 shRNA Plasmid (Human) - CHH3328 from Cohesion Biosciences
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OTX1 miRNA 3'UTR clone - MiUTR3H-03089 from Creative biogene
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