| Gene Symbol |
RAD54L
|
| Entrez Gene |
8438
|
| Alt Symbol |
HR54, RAD54A, hHR54, hRAD54
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
RAD54-like (S. cerevisiae)
|
| Other Description |
DNA repair and recombination protein RAD54-like|RAD54 homolog
|
| Swissprots |
Q5TE31 Q6IUY3 Q92698
|
| Accessions |
AAT38113 CCQ43221 EAX06929 EAX06930 Q92698 AA582917 AK292611 BAF85300 AK297204 BAG59689 BC121059 AAI21060 BC121060 AAI21061 BM464345 BM678712 DB048280 DB449264 X97795 CAA66379 XM_006710975 XP_006711038 XM_011542299 XP_011540601 XM_011542300 XP_011540602 NM_001142548 NP_001136020 NM_003579 NP_003570
|
| Function |
Involved in DNA repair and mitotic recombination. Functions in the recombinational DNA repair (RAD52) pathway. Dissociates RAD51 from nucleoprotein filaments formed on dsDNA. Could be involved in the turnover of RAD51 protein-dsDNA filaments (By similarity). May play also an essential role in telomere length maintenance and telomere capping in mammalian cells. {ECO:0000250, ECO:0000269|PubMed:11459989, ECO:0000269|PubMed:12205100, ECO:0000269|PubMed:9774452}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:8805304}.
|
| Top Pathways |
Homologous recombination
|
![Western Blot: RAD54L Overexpression Lysate (Adult Normal) [NBP2-07980] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for RAD54L.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/24420_RAD54L%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBP2-07980-img0001.jpg)
![Western Blot: RAD54L Overexpression Lysate (Adult Normal) [NBP2-09658] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for RAD54L.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4446_RAD54L%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-09658-img0001.jpg)