Gene Symbol | PPP1R1C |
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Entrez Gene | 151242 |
Alt Symbol | IPP5 |
Species | Human |
Gene Type | protein-coding |
Description | protein phosphatase 1, regulatory (inhibitor) subunit 1C |
Other Description | PP1 inhibitor protein 5|inhibitor-5 of protein phosphatase 1|protein phosphatase 1 regulatory subunit 1A|protein phosphatase 1 regulatory subunit 1C |
Swissprots | Q5HYJ5 Q8WVI7 Q8TD54 |
Accessions | AAY14914 AAY24129 EAX10976 EAX10977 Q8WVI7 AA321774 AF494535 AAM18054 AK129898 AK311322 AK311571 BC017943 AAH17943 BI792375 BX647581 CAI46089 NM_001080545 NP_001074014 NM_001261424 NP_001248353 NM_001261425 NP_001248354 NR_048566 NR_048567 |
Function | Inhibitor of protein-phosphatase 1. Promotes cell growth and cell cycle progress at the G1/S transition. May increase cell susceptibility to TNF-induced apoptosis. {ECO:0000269|PubMed:18310074, ECO:0000269|PubMed:19874272}. |
Subcellular Location | Cytoplasm {ECO:0000250}. |
Tissue Specificity | Expressed in heart, skeletal muscle, liver and testis (at protein level). |
PPP1R1C CRISPR/Cas9 KO Plasmid (h) - sc-410338 from Santa Cruz Biotechnology
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PPP1R1C HDR Plasmid (h) - sc-410338-HDR from Santa Cruz Biotechnology
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PPP1R1C Double Nickase Plasmid (h) - sc-410338-NIC from Santa Cruz Biotechnology
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PPP1R1C Double Nickase Plasmid (h2) - sc-410338-NIC-2 from Santa Cruz Biotechnology
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PPP1R1C CRISPR Activation Plasmid (h) - sc-410338-ACT from Santa Cruz Biotechnology
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PPP1R1C CRISPR Activation Plasmid (h2) - sc-410338-ACT-2 from Santa Cruz Biotechnology
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PPP1R1C Lentiviral Activation Particles (h) - sc-410338-LAC from Santa Cruz Biotechnology
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PPP1R1C Lentiviral Activation Particles (h2) - sc-410338-LAC-2 from Santa Cruz Biotechnology
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PPP1R1C siRNA (h) - sc-94330 from Santa Cruz Biotechnology
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PPP1R1C shRNA Plasmid (h) - sc-94330-SH from Santa Cruz Biotechnology
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PPP1R1C shRNA (h) Lentiviral Particles - sc-94330-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU152621 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17274 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17274 from Sigma-Aldrich
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PPP1R1C siRNA (Human) - CRJ5689 from Cohesion Biosciences
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shRNA set against Human PPP1R1C (NM_001080545.2) - SHH381184 from Creative biogene
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PPP1R1C shRNA Plasmid (Human) - CHJ5689 from Cohesion Biosciences
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