| Gene Symbol | DAO |
|---|---|
| Entrez Gene | 100008977 |
| Alt Symbol | - |
| Species | Rabbit |
| Gene Type | protein-coding |
| Description | D-amino-acid oxidase |
| Other Description | D-amino acid oxidase|DAAO|DAMOX |
| Swissprots | P22942 |
| Accessions | P22942 D12494 BAA02058 NM_001082189 NP_001075658 |
| Function | Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D- amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids (By similarity). {ECO:0000250}. |
| Subcellular Location | Peroxisome. |
| Top Pathways | Glycine, serine and threonine metabolism, Peroxisome, Arginine and proline metabolism, D-Arginine and D-ornithine metabolism |