| Gene Symbol |
DAO
|
| Entrez Gene |
100008977
|
| Alt Symbol |
-
|
| Species |
Rabbit
|
| Gene Type |
protein-coding
|
| Description |
D-amino-acid oxidase
|
| Other Description |
D-amino acid oxidase|DAAO|DAMOX
|
| Swissprots |
P22942
|
| Accessions |
P22942 D12494 BAA02058 NM_001082189 NP_001075658
|
| Function |
Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D- amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Peroxisome.
|
| Top Pathways |
Glycine, serine and threonine metabolism, Peroxisome, Arginine and proline metabolism, D-Arginine and D-ornithine metabolism
|