Gene Symbol | RIPPLY3 |
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Entrez Gene | 53820 |
Alt Symbol | DSCR6 |
Species | Human |
Gene Type | protein-coding |
Description | ripply transcriptional repressor 3 |
Other Description | Down syndrome critical region gene 6|down syndrome critical region protein 6|protein ripply3|ripply3 homolog |
Swissprots | P57055 |
Accessions | EAX09729 EAX09730 P57055 AB037158 BAA96867 AB037159 BAA96868 AB037160 BAA96869 AB037161 BAA96870 BC146275 AAI46276 BC156711 AAI56712 XM_005260993 XP_005261050 NM_018962 NP_061835 |
Function | Acts as a transcriptional corepressor. Negative regulator of the transcriptional activity of TBX1. Plays a role in the development of the pharyngeal apparatus and derivatives (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000250}. |
Tissue Specificity | Expressed at a low level in fetal kidney and fetal brain. {ECO:0000269|PubMed:10814524}. |
DSCR 6 CRISPR/Cas9 KO Plasmid (h) - sc-412253 from Santa Cruz Biotechnology
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DSCR 6 HDR Plasmid (h) - sc-412253-HDR from Santa Cruz Biotechnology
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DSCR 6 Double Nickase Plasmid (h) - sc-412253-NIC from Santa Cruz Biotechnology
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DSCR 6 Double Nickase Plasmid (h2) - sc-412253-NIC-2 from Santa Cruz Biotechnology
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DSCR 6 CRISPR Activation Plasmid (h) - sc-412253-ACT from Santa Cruz Biotechnology
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DSCR 6 CRISPR Activation Plasmid (h2) - sc-412253-ACT-2 from Santa Cruz Biotechnology
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DSCR 6 Lentiviral Activation Particles (h) - sc-412253-LAC from Santa Cruz Biotechnology
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DSCR 6 Lentiviral Activation Particles (h2) - sc-412253-LAC-2 from Santa Cruz Biotechnology
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DSCR 6 siRNA (h) - sc-40499 from Santa Cruz Biotechnology
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DSCR 6 shRNA Plasmid (h) - sc-40499-SH from Santa Cruz Biotechnology
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DSCR 6 shRNA (h) Lentiviral Particles - sc-40499-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU089201 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7504 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7504 from Sigma-Aldrich
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RIPPLY3 siRNA (Human) - CRH9980 from Cohesion Biosciences
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RIPPLY3 - MBS8204382 from MyBioSource
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shRNA set against Human DSCR6 (NM_018962.2) - SHH281209 from Creative biogene
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RIPPLY3 shRNA Plasmid (Human) - CHH9980 from Cohesion Biosciences
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