Gene Symbol | CHRNG |
---|---|
Entrez Gene | 1146 |
Alt Symbol | ACHRG |
Species | Human |
Gene Type | protein-coding |
Description | cholinergic receptor, nicotinic, gamma (muscle) |
Other Description | acetylcholine receptor subunit gamma|acetylcholine receptor, muscle, gamma subunit|acetylcholine receptor, nicotinic, gamma (muscle)|cholinergic receptor, nicotinic, gamma polypeptide |
Swissprots | Q53RG2 P07510 B3KWM8 Q14DU4 |
Accessions | AAY24103 CAA25861 EAW71004 EAW71005 P07510 AK125362 BAG54190 AK309340 BC111802 AAI11803 NM_005199 NP_005190 |
Function | After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. |
Subcellular Location | Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. |
Top Pathways | Neuroactive ligand-receptor interaction |