Gene Symbol | TRMT61B |
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Entrez Gene | 55006 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | tRNA methyltransferase 61B |
Other Description | potential tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61B|potential tRNA (adenine-N(1)-)-methyltransferase catalytic subunit TRMT61B|tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial|tRNA methyltransferase 61 homolog B |
Swissprots | Q9NWS7 Q9BVS5 Q9H0Q9 |
Accessions | AAY24015 EAX00524 EAX00525 Q9BVS5 AK225524 AK225551 AL136689 CAB66624 BC000952 AAH00952 BC010365 AAH10365 HQ448250 ADQ32730 XM_005264393 XP_005264450 XM_005264394 XP_005264451 XM_006712037 XP_006712100 XM_011532938 XP_011531240 XR_244945 XR_939691 NM_017910 NP_060380 |
Function | Methyltransferase that catalyzes the formation of N(1)- methyladenine at position 58 (m1A58) in various tRNAs in mitochondrion, including tRNA(Leu) (decephering codons UUA or UUG), tRNA(Lys) and tRNA(Ser) (decephering codons UCA, UCU, UCG or UCC). {ECO:0000269|PubMed:23097428}. |
Subcellular Location | Mitochondrion {ECO:0000269|PubMed:23097428}. |
TRMT61B CRISPR/Cas9 KO Plasmid (h) - sc-412411 from Santa Cruz Biotechnology
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TRMT61B HDR Plasmid (h) - sc-412411-HDR from Santa Cruz Biotechnology
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TRMT61B Double Nickase Plasmid (h) - sc-412411-NIC from Santa Cruz Biotechnology
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TRMT61B Double Nickase Plasmid (h2) - sc-412411-NIC-2 from Santa Cruz Biotechnology
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TRMT61B CRISPR Activation Plasmid (h) - sc-412411-ACT from Santa Cruz Biotechnology
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TRMT61B CRISPR Activation Plasmid (h2) - sc-412411-ACT-2 from Santa Cruz Biotechnology
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TRMT61B Lentiviral Activation Particles (h) - sc-412411-LAC from Santa Cruz Biotechnology
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TRMT61B Lentiviral Activation Particles (h2) - sc-412411-LAC-2 from Santa Cruz Biotechnology
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TRMT61B siRNA (h) - sc-94357 from Santa Cruz Biotechnology
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TRMT61B shRNA Plasmid (h) - sc-94357-SH from Santa Cruz Biotechnology
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TRMT61B shRNA (h) Lentiviral Particles - sc-94357-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU010351 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22043 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22043 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03854 from Sigma-Aldrich
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TRMT61B siRNA (Human) - CRJ0399 from Cohesion Biosciences
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TRMT61B - MBS8223616 from MyBioSource
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shRNA set against Human TRMT61B (NM_017910.3) - SHH435368 from Creative biogene
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Human TRMT61B siRNA - orb270900 from Biorbyt
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TRMT61B shRNA Plasmid (Human) - CHJ0399 from Cohesion Biosciences
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TRMT61B miRNA 3'UTR clone - MiUTR3H-16410 from Creative biogene
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