Gene Symbol | NPR3 |
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Entrez Gene | 4883 |
Alt Symbol | ANP-C, ANPR-C, ANPRC, C5orf23, GUCY2B, NPR-C, NPRC |
Species | Human |
Gene Type | protein-coding |
Description | natriuretic peptide receptor 3 |
Other Description | atrial natriuretic peptide clearance receptor|atrial natriuretic peptide receptor 3|atrial natriuretic peptide receptor type C|atrionatriuretic peptide receptor C|guanylate cyclase C|natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) |
Swissprots | E7EPG9 B4DT84 A2RRD1 P17342 |
Accessions | BAC56126 EAX10797 EAX10798 EAX10799 EAX10800 P17342 AF025998 AAB88801 AI335695 AK024116 BAB14832 AK290870 BAF83559 AK300094 BAG61896 AK308301 BC022250 AAH22250 BC131540 AAI31541 BF224187 BQ014050 M59305 AAA51734 X52282 CAA36523 XM_005248309 XP_005248366 XM_005248310 XP_005248367 XM_011514047 XP_011512349 XM_011514048 XP_011512350 XM_011514049 XP_011512351 XM_011514050 XP_011512352 NM_000908 NP_000899 NM_001204375 NP_001191304 NM_001204376 NP_001191305 NM_024563 |
Function | Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
NPR-C CRISPR/Cas9 KO Plasmid (h) - sc-403893 from Santa Cruz Biotechnology
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NPR-C HDR Plasmid (h) - sc-403893-HDR from Santa Cruz Biotechnology
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NPR-C Double Nickase Plasmid (h) - sc-403893-NIC from Santa Cruz Biotechnology
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NPR-C Double Nickase Plasmid (h2) - sc-403893-NIC-2 from Santa Cruz Biotechnology
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NPR-C CRISPR Activation Plasmid (h) - sc-403893-ACT from Santa Cruz Biotechnology
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NPR-C CRISPR Activation Plasmid (h2) - sc-403893-ACT-2 from Santa Cruz Biotechnology
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NPR-C Lentiviral Activation Particles (h) - sc-403893-LAC from Santa Cruz Biotechnology
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NPR-C Lentiviral Activation Particles (h2) - sc-403893-LAC-2 from Santa Cruz Biotechnology
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NPR-C siRNA (h) - sc-40129 from Santa Cruz Biotechnology
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NPR-C shRNA Plasmid (h) - sc-40129-SH from Santa Cruz Biotechnology
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NPR-C shRNA (h) Lentiviral Particles - sc-40129-V from Santa Cruz Biotechnology
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C5orf23 siRNA (h) - sc-91931 from Santa Cruz Biotechnology
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C5orf23 shRNA Plasmid (h) - sc-91931-SH from Santa Cruz Biotechnology
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Natriuretic Peptide Receptor C RNAi - H00004883-R02 from Novus Biologicals
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MISSION® esiRNA - EHU037441 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15468 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15468 from Sigma-Aldrich
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NPR3 siRNA (Human) - CRH3244 from Cohesion Biosciences
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shRNA set against Human NPR3 (NM_000908.3) - SHH354416 from Creative biogene
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Human NPR3 siRNA - orb263746 from Biorbyt
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NPR3 shRNA Plasmid (Human) - CHH3244 from Cohesion Biosciences
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NPR3 miRNA 3'UTR clone - MiUTR3H-00228 from Creative biogene
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