Gene Symbol | EIF4A2 |
---|---|
Entrez Gene | 1974 |
Alt Symbol | BM-010, DDX2B, EIF4A, EIF4F, eIF-4A-II, eIF4A-II |
Species | Human |
Gene Type | protein-coding |
Description | eukaryotic translation initiation factor 4A2 |
Other Description | ATP-dependent RNA helicase eIF4A-2|eukaryotic initiation factor 4A-II |
Swissprots | Q53XJ6 Q14240 Q96EA8 D3DNU9 Q96B90 |
Accessions | EAW78172 EAW78173 EAW78174 EAW78175 EAW78176 EAW78177 EAW78178 Q14240 AB209021 BAD92258 AF208852 AAF64266 AK130087 AK225646 AK296279 BAG58988 AL117412 CAI46218 AL137681 AL556981 AY207392 AAO66460 BC006469 BC012547 AAH12547 BC013708 AAH13708 BC015842 AAH15842 BC016295 AAH16295 BC039344 BC048105 AAH48105 BT009860 AAP88862 D30655 BAA06336 DQ891738 ABM82664 DQ894914 ABM85840 S79942 NM_001967 NP_001958 |
Function | ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon. |
Top Pathways | RNA transport |
eIF4AII CRISPR/Cas9 KO Plasmid (h) - sc-402758 from Santa Cruz Biotechnology
|
||||||||
eIF4AII HDR Plasmid (h) - sc-402758-HDR from Santa Cruz Biotechnology
|
||||||||
eIF4AII Double Nickase Plasmid (h) - sc-402758-NIC from Santa Cruz Biotechnology
|
||||||||
eIF4AII Double Nickase Plasmid (h2) - sc-402758-NIC-2 from Santa Cruz Biotechnology
|
||||||||
eIF4AII CRISPR Activation Plasmid (h) - sc-402758-ACT from Santa Cruz Biotechnology
|
||||||||
eIF4AII CRISPR Activation Plasmid (h2) - sc-402758-ACT-2 from Santa Cruz Biotechnology
|
||||||||
eIF4AII Lentiviral Activation Particles (h) - sc-402758-LAC from Santa Cruz Biotechnology
|
||||||||
eIF4AII Lentiviral Activation Particles (h2) - sc-402758-LAC-2 from Santa Cruz Biotechnology
|
||||||||
eIF4AII siRNA (h) - sc-40556 from Santa Cruz Biotechnology
|
||||||||
eIF4AII shRNA Plasmid (h) - sc-40556-SH from Santa Cruz Biotechnology
|
||||||||
eIF4AII shRNA (h) Lentiviral Particles - sc-40556-V from Santa Cruz Biotechnology
|
||||||||
eIF4A2 RNAi - H00001974-R02 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU115391 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN7772 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7772 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR04750 from Sigma-Aldrich
|
||||||||
EIF4A2 siRNA (Human) - CRH1365 from Cohesion Biosciences
|
||||||||
EIF4A2 - MBS8236350 from MyBioSource
|
||||||||
shRNA set against Human EIF4A2 (NM_001967.3) - SHH284601 from Creative biogene
|
||||||||
shRNA set against Human EIF4A2(NM_001967.3) - SHH029513 from Creative biogene
|
||||||||
Human EIF4A2 siRNA - orb261867 from Biorbyt
|
||||||||
EIF4A2 shRNA Plasmid (Human) - CHH1365 from Cohesion Biosciences
|
||||||||
EIF4A2 miRNA 3'UTR clone - MiUTR1H-03171 from Creative biogene
|