| Gene Symbol |
INMT
|
| Entrez Gene |
100008695
|
| Alt Symbol |
-
|
| Species |
Rabbit
|
| Gene Type |
protein-coding
|
| Description |
indolethylamine N-methyltransferase
|
| Other Description |
amine N-methyltransferase|aromatic alkylamine N-methyltransferase|arylamine N-methyltransferase|indolamine N-methyltransferase|thioether S-methyltransferase
|
| Swissprots |
O97972
|
| Accessions |
AAC97492 O97972 AF077826 AAC97491 GBCK01061938 NM_001082043 NP_001075512
|
| Function |
Catalyzes the N-methylation of tryptamine and structurally related compounds (By similarity). Functions as thioether S-methyltransferase and is active with a variety of thioethers and the corresponding selenium and tellurium compounds, including 3-methylthiopropionaldehyde, dimethyl selenide, dimethyl telluride, 2-methylthioethylamine, 2-methylthioethanol, methyl-n- propyl sulfide and diethyl sulfide. Plays an important role in the detoxification of selenium compounds (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm.
|
| Tissue Specificity |
Highly expressed in lung, also detected in liver and at very low levels in brain.
|
| Top Pathways |
Tryptophan metabolism, Selenocompound metabolism
|