| Gene Symbol | DNAJC13 |
|---|---|
| Entrez Gene | 23317 |
| Alt Symbol | RME8 |
| Species | Human |
| Gene Type | protein-coding |
| Description | DnaJ (Hsp40) homolog, subfamily C, member 13 |
| Other Description | DnaJ domain-containing protein RME-8|RME-8|dnaJ homolog subfamily C member 13|required for receptor-mediated endocytosis 8 |
| Swissprots | Q9BWK9 Q86XG3 Q6ZUT5 O75165 Q3L0T1 Q96DC1 Q6PI82 Q6ZSW1 Q6UJ77 |
| Accessions | EAW79198 EAW79199 O75165 AB014578 BAA31653 AI189887 AK023168 BAG51164 AK098729 BAC05394 AK125330 BAC86133 AK127112 BAC86835 AY369172 AAQ57271 AY779857 AAV41096 BC000164 AAH00164 BC009630 AAH09630 BC033782 BC040638 AAH40638 BC043583 AAH43583 BC065756 BC105580 AAI05581 BC151246 AAI51247 XM_005247245 XP_005247302 NM_015268 NP_056083 |
| Function | Involved in membrane trafficking through early endosomes, such as the early endosome to recycling endosome transport implicated in the recycling of transferrin and the early endosome to late endosome transport implicated in degradation of EGF and EGFR (PubMed:18256511, PubMed:18307993). Involved in the regulation of endosomal membrane tubulation and regulates th dynamics of SNX1 on the endosomal membrane; via association with FAM21 may link the WASH complex to the retromer SNX-BAR subcomplex (PubMed:24643499). {ECO:0000269|PubMed:18256511, ECO:0000269|PubMed:18307993, ECO:0000269|PubMed:24643499}. |
| Subcellular Location | Early endosome {ECO:0000269|PubMed:18256511}. Early endosome membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000269|PubMed:18256511}. Endosome membrane {ECO:0000269|PubMed:24643499}. |
DnaJC13 CRISPR/Cas9 KO Plasmid (h) - sc-411713 from Santa Cruz Biotechnology
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DnaJC13 HDR Plasmid (h) - sc-411713-HDR from Santa Cruz Biotechnology
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DnaJC13 Double Nickase Plasmid (h) - sc-411713-NIC from Santa Cruz Biotechnology
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DnaJC13 Double Nickase Plasmid (h2) - sc-411713-NIC-2 from Santa Cruz Biotechnology
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DnaJC13 CRISPR Activation Plasmid (h) - sc-411713-ACT from Santa Cruz Biotechnology
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DnaJC13 CRISPR Activation Plasmid (h2) - sc-411713-ACT-2 from Santa Cruz Biotechnology
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DnaJC13 Lentiviral Activation Particles (h) - sc-411713-LAC from Santa Cruz Biotechnology
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DnaJC13 Lentiviral Activation Particles (h2) - sc-411713-LAC-2 from Santa Cruz Biotechnology
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DnaJC13 siRNA (h) - sc-77968 from Santa Cruz Biotechnology
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DnaJC13 shRNA Plasmid (h) - sc-77968-SH from Santa Cruz Biotechnology
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DnaJC13 shRNA (h) Lentiviral Particles - sc-77968-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU006591 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7361 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7361 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06995 from Sigma-Aldrich
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DNAJC13 siRNA (Human) - CRH8176 from Cohesion Biosciences
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DNAJC13 - MBS8208717 from MyBioSource
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shRNA set against Human DNAJC13 (NM_015268.3) - SHH279465 from Creative biogene
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shRNA set against Human DNAJC13(NM_015268.3) - SHH010433 from Creative biogene
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DnaJC13 CRISPR/Cas9 KO Plasmid (h2) - sc-411713-KO-2 from Santa Cruz Biotechnology
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DnaJC13 HDR Plasmid (h2) - sc-411713-HDR-2 from Santa Cruz Biotechnology
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DNAJC13 shRNA Plasmid (Human) - CHH8176 from Cohesion Biosciences
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DNAJC13 miRNA 3'UTR clone - MiUTR1H-02919 from Creative biogene
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