Gene Symbol |
SIGLEC9
|
Entrez Gene |
27180
|
Alt Symbol |
CD329, CDw329, FOAP-9, OBBP-LIKE, siglec-9
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
sialic acid binding Ig-like lectin 9
|
Other Description |
protein FOAP-9|sialic acid-binding Ig-like lectin 9
|
Swissprots |
Q9BYI9 Q9Y336 Q6GTU4
|
Accessions |
AAD26428 AAG23261 AAS89011 EAW71985 Q9Y336 AB026265 BAB41100 AF227924 AAF71455 AF247180 AAF87223 AK297043 BAG59570 AK315272 AY358913 AAQ89272 BC035365 AAH35365 BP305376 DQ892476 ABM83402 DQ895688 ABM86614 XM_006723146 XP_006723209 XM_011526730 XP_011525032 XM_011526731 XP_011525033 XM_011526732 XP_011525034 XM_011526733 XP_011525035 XR_935794 NM_001198558 NP_001185487 NM_014441 NP_055256
|
Function |
Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- or alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
|
Subcellular Location |
Membrane; Single-pass type I membrane protein.
|
Tissue Specificity |
Expressed by peripheral blood leukocytes (neutrophils and monocytes but not eosinophils). Found in liver, fetal liver, bone marrow, placenta, spleen and in lower levels in skeletal muscle, fetal brain, stomach, lung, thymus, prostate, brain, mammary, adrenal gland, colon, trachea, cerebellum, testis, small intestine and spinal cordon.
|