| Gene Symbol | FPGS |
|---|---|
| Entrez Gene | 505809 |
| Alt Symbol | - |
| Species | Bovine |
| Gene Type | protein-coding |
| Description | folylpolyglutamate synthase |
| Other Description | folylpoly-gamma-glutamate synthetase|folylpolyglutamate synthase, mitochondrial|tetrahydrofolate synthase|tetrahydrofolylpolyglutamate synthase |
| Swissprots | A6H751 |
| Accessions | A6H751 DAA24139 BC146114 AAI46115 BE666530 BT021744 AAX46591 CO888657 XM_005213422 XP_005213479 NM_001024480 NP_001019651 |
| Function | Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis. {ECO:0000250}. |
| Subcellular Location | Mitochondrion inner membrane {ECO:0000250}. Mitochondrion matrix {ECO:0000250}. Cytoplasm {ECO:0000250}. |
| Top Pathways | Folate biosynthesis |
folylpolyglutamate synthase, ELISA Kit - MBS9343141 from MyBioSource
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Bovine FPGS ELISA Kit - E083523 from Biobool
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Folylpolyglutamate synthase, mitochondrial (FPGS), ELISA Kit - MBS287659 from MyBioSource
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