Gene Symbol | DDX39A |
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Entrez Gene | 10212 |
Alt Symbol | BAT1, BAT1L, DDX39, DDXL, URH49 |
Species | Human |
Gene Type | protein-coding |
Description | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A |
Other Description | ATP-dependent RNA helicase DDX39A|DEAD (Asp-Glu-Ala-Asp) box polypeptide 39|DEAD box protein 39|DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 39|UAP56-related helicase, 49 kDa|nuclear RNA helicase URH49|nuclear RNA helicase, DECD variant of DEAD box family |
Swissprots | Q9BVP6 Q9H5W0 B1Q2N1 O00148 Q8N5M0 |
Accessions | EAW84414 EAW84415 EAW84416 EAW84417 EAW84418 O00148 AB254849 BAG16272 AK293911 BAG57295 AK301847 BAG63290 AL512698 CAH10601 BC001009 AAH01009 BC010455 BC032128 AAH32128 BM792110 DA432925 DB032777 DQ891387 ABM82313 DQ894563 ABM85489 U90426 AAB50231 XM_006722606 XP_006722669 XM_011527620 XP_011525922 XM_011527621 XP_011525923 NM_005804 NP_005795 NR_046366 NM_001204057 NM_138998 NR_038336 |
Function | Isoform 1: Involved in pre-mRNA splicing. Required for the export of mRNA out of the nucleus. {ECO:0000269|PubMed:15047853, ECO:0000269|PubMed:17548965}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:21859714}. Cytoplasm {ECO:0000269|PubMed:21859714}. Note=Can translocate to the cytoplasm in the presence of MX1. |
Tissue Specificity | Detected in testis, and at lower levels in brain, kidney, lung, thymus, spleen and salivary gland. {ECO:0000269|PubMed:15047853}. |
DDX39 CRISPR/Cas9 KO Plasmid (h) - sc-411433 from Santa Cruz Biotechnology
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DDX39 HDR Plasmid (h) - sc-411433-HDR from Santa Cruz Biotechnology
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DDX39 Double Nickase Plasmid (h) - sc-411433-NIC from Santa Cruz Biotechnology
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DDX39 Double Nickase Plasmid (h2) - sc-411433-NIC-2 from Santa Cruz Biotechnology
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DDX39 CRISPR Activation Plasmid (h) - sc-411433-ACT from Santa Cruz Biotechnology
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DDX39 CRISPR Activation Plasmid (h2) - sc-411433-ACT-2 from Santa Cruz Biotechnology
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DDX39 Lentiviral Activation Particles (h) - sc-411433-LAC from Santa Cruz Biotechnology
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DDX39 Lentiviral Activation Particles (h2) - sc-411433-LAC-2 from Santa Cruz Biotechnology
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DDX39 siRNA (h) - sc-77111 from Santa Cruz Biotechnology
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DDX39 shRNA Plasmid (h) - sc-77111-SH from Santa Cruz Biotechnology
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DDX39 shRNA (h) Lentiviral Particles - sc-77111-V from Santa Cruz Biotechnology
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DDX39 RNAi - H00010212-R03 from Novus Biologicals
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DDX39 RNAi - H00010212-R04 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN7053 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7053 from Sigma-Aldrich
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DDX39A siRNA (Human) - CRH6901 from Cohesion Biosciences
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DDX39A - MBS8207826 from MyBioSource
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shRNA set against Human DDX39A (NM_005804.3) - SHH275981 from Creative biogene
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DDX39A shRNA Plasmid (Human) - CHH6901 from Cohesion Biosciences
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DDX39A miRNA 3'UTR clone - MiUTR3H-13554 from Creative biogene
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