| Gene Symbol |
NAA60
|
| Entrez Gene |
79903
|
| Alt Symbol |
HAT4, NAT15
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
N(alpha)-acetyltransferase 60, NatF catalytic subunit
|
| Other Description |
N-acetyltransferase 15 (GCN5-related, putative)|N-alpha-acetyltransferase 60|histone acetyltransferase type B protein 4|natF catalytic subunit
|
| Swissprots |
B4DYC4 Q6UX26 B3KRQ0 Q9H7X0 B4DLZ0 B4DPZ8 E7EQ65 Q6IA31 D3DUC2
|
| Accessions |
CAE92069 EAW85358 EAW85359 EAW85360 EAW85361 EAW85362 EAW85363 EAW85364 Q9H7X0 AK021755 AK024216 BAB14853 AK092005 BAG52462 AK095819 AK130792 AK225178 AK297219 BAG59702 AK298566 BAG60760 AK302361 BAG63686 AK311524 AL833594 AY358543 AAQ88907 BC011267 AAH11267 BG472911 BU501490 CR457324 CAG33605 DA736660 DA786716 HQ447122 ADQ31609 XM_011522660 XP_011520962 XM_011522661 XP_011520963 XM_011522662 XP_011520964 XM_011522663 XP_011520965 XM_011522664 XP_011520966 XM_011522665 XP_011520967 XR_932932 NM_001083600 NP_001077069 NM_001083601 NP_001077070 NM_024845 NP_079121
|
| Function |
Histone acetyltransferase localized in the Golgi apparatus that mediates acetylation of free histone H4, thereby facilitating nucleosome assembly. Has a preference for free histone H4 'Lys-20'(H4K20ac), 'Lys-79'(H4K79ac) and 'Lys-91' (H4K91ac). Also displays alpha (N-terminal) acetyltransferase activity towards a range of N-terminal sequences including those starting with Met-Lys, Met-Val, Met-Ala and Met-Met. Required for normal chromosomal segregation during anaphase. {ECO:0000269|PubMed:21750686, ECO:0000269|PubMed:21981917}.
|
| Subcellular Location |
Golgi apparatus membrane {ECO:0000269|PubMed:21981917}.
|