| Gene Symbol | HNRNPA1 |
|---|---|
| Entrez Gene | 3178 |
| Alt Symbol | ALS19, ALS20, HNRPA1, HNRPA1L3, IBMPFD3, hnRNP A1, hnRNP-A1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | heterogeneous nuclear ribonucleoprotein A1 |
| Other Description | Putative heterogeneous nuclear ribonucleoprotein A1-like 3|helix-destabilizing protein|heterogeneous nuclear ribonucleoprotein A1B protein|heterogeneous nuclear ribonucleoprotein B2 protein|heterogeneous nuclear ribonucleoprotein core protein A1|hnRNP A1-like 3|hnRNP core protein A1|hnRNP core protein A1-like 3|nuclear ribonucleoprotein particle A1 protein|single-strand DNA-binding protein UP1|single-strand RNA-binding protein |
| Swissprots | Q6PJZ7 P09651 A8K4Z8 Q3MIB7 |
| Accessions | CAA31191 EAW96761 EAW96762 EAW96763 EAW96764 EAW96765 EAW96766 EAW96767 EAW96768 EAW96769 EAW96770 P09651 AK129814 AK291113 BAF83802 AK298176 BAG60447 AK303303 BAG64377 AK308679 BC002355 AAH02355 BC004945 AAH04945 BC009600 AAH09600 BC012158 AAH12158 BC020442 BC033714 AAH33714 BC035253 BC052296 AAH52296 BC070315 AAH70315 BC071945 AAH71945 BC073162 AAH73162 BC074502 AAH74502 BC078165 BC103707 AAI03708 BC104236 AAI04237 BC104237 AAI04238 BC121133 AAI21134 BQ277208 BU501222 BX425482 CD705336 CF541085 U00947 X04347 CAA27874 X06747 CAA29922 X79536 CAA56072 XM_005268826 XP_005268883 XR_245923 XR_245924 NM_002136 NP_002127 NM_031157 NP_112420 |
| Function | Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection. May play a role in HCV RNA replication. {ECO:0000269|PubMed:17229681}. |
| Subcellular Location | Nucleus. Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Shuttles continuously between the nucleus and the cytoplasm along with mRNA. Component of ribonucleosomes. In the course of viral infection, colocalizes with HCV NS5B at speckles in the cytoplasm in a HCV-replication dependent manner. |
| Top Pathways | Spliceosome |