| Gene Symbol |
PHYKPL
|
| Entrez Gene |
85007
|
| Alt Symbol |
AGXT2L2, PHLU
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
5-phosphohydroxy-L-lysine phospho-lyase
|
| Other Description |
5-phosphonooxy-L-lysine phospho-lyase|alanine--glyoxylate aminotransferase 2-like 2|alanine-glyoxylate aminotransferase 2-like 2
|
| Swissprots |
B3KN36 D3DWP9 Q8IUZ5 Q8WYS6 Q96HW8 A8K7P6
|
| Accessions |
EAW53835 EAW53836 EAW53837 EAW53838 EAW53839 EAW53840 EAW53841 Q8IUZ5 AA862441 AF318375 AAL55882 AK023470 BAG51198 AK024076 AK090397 BAC03378 AK093737 AK292061 BAF84750 BC008009 AAH08009 BC028002 BC037238 BC037567 AAH37567 BC039012 BC067745 BC088800 BC110335 AAI10336 BX417194 DB022121 HQ447303 ADQ31790 HY267487 JF432620 ADZ15837 XM_005266002 XP_005266059 XM_006714925 XP_006714988 XM_006714926 XP_006714989 XM_011534669 XP_011532971 XM_011534670 XP_011532972 XM_011534671 XP_011532973 XM_011534672 XP_011532974 XM_011534673 XP_011532975 XM_011534674 XP_011532976 XM_011534675 XP_011532977 XM_011534676 XP_011532978 XM_011534677 XP_011532979 XM_011534678 XP_011532980 XM_011534679 XP_011532981 XR_427812 XR_941114 XR_941115 XR_941116 XR_941117 NM_001278346 NP_001265275 NM_153373 NP_699204 NR_103508 NR_103509 NR_103510
|
| Function |
Catalyzes the pyridoxal-phosphate-dependent breakdown of 5-phosphohydroxy-L-lysine, converting it to ammonia, inorganic phosphate and 2-aminoadipate semialdehyde. {ECO:0000269|PubMed:22241472}.
|
| Subcellular Location |
Mitochondrion {ECO:0000305}.
|
| Top Pathways |
Lysine degradation
|
![Western Blot: AGXT2L2 Overexpression Lysate (Adult Normal) [NBL1-07401] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for AGXT2L2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6255_AGXT2L2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-07401-img0002.jpg)