Gene Symbol | TAS2R16 |
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Entrez Gene | 50833 |
Alt Symbol | T2R16 |
Species | Human |
Gene Type | protein-coding |
Description | taste receptor, type 2, member 16 |
Other Description | candidate taste receptor T2R16|taste receptor type 2 member 16 |
Swissprots | Q502V3 A4D0X2 Q549U8 Q645W1 Q9NYV7 |
Accessions | AAF43912 AAP21892 BAD98011 BAD98012 BAD98013 CAI53565 CAV28566 EAL24338 EAW83581 Q9NYV7 BC095524 AAH95524 NM_016945 NP_058641 |
Function | Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. {ECO:0000269|PubMed:12379855, ECO:0000269|PubMed:15759003}. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed in a subset of gustducin-positive taste receptor cells of the tongue. |
Top Pathways | Taste transduction |
T2R16 CRISPR/Cas9 KO Plasmid (h) - sc-408593 from Santa Cruz Biotechnology
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T2R16 HDR Plasmid (h) - sc-408593-HDR from Santa Cruz Biotechnology
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T2R16 Double Nickase Plasmid (h) - sc-408593-NIC from Santa Cruz Biotechnology
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T2R16 Double Nickase Plasmid (h2) - sc-408593-NIC-2 from Santa Cruz Biotechnology
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T2R16 CRISPR Activation Plasmid (h) - sc-408593-ACT from Santa Cruz Biotechnology
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T2R16 CRISPR Activation Plasmid (h2) - sc-408593-ACT-2 from Santa Cruz Biotechnology
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T2R16 Lentiviral Activation Particles (h) - sc-408593-LAC from Santa Cruz Biotechnology
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T2R16 Lentiviral Activation Particles (h2) - sc-408593-LAC-2 from Santa Cruz Biotechnology
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T2R16 siRNA (h) - sc-89454 from Santa Cruz Biotechnology
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T2R16 shRNA Plasmid (h) - sc-89454-SH from Santa Cruz Biotechnology
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T2R16 shRNA (h) Lentiviral Particles - sc-89454-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU004631 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21016 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21016 from Sigma-Aldrich
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TAS2R16 siRNA (Human) - CRH9414 from Cohesion Biosciences
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TAS2R16 RNAi - H00050833-R02 from Novus Biologicals
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TAS2R16 - MBS8228538 from MyBioSource
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shRNA set against Human TAS2R16 (NM_016945.2) - SHH423496 from Creative biogene
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shRNA set against Human TAS2R16(NM_016945.2) - SHL057540 from Creative biogene
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TAS2R16 shRNA Plasmid (Human) - CHH9414 from Cohesion Biosciences
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TAS2R16 miRNA 3'UTR clone - MiUTR1H-10194 from Creative biogene
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