| Gene Symbol |
DLG5
|
| Entrez Gene |
9231
|
| Alt Symbol |
LP-DLG, P-DLG5, PDLG
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
discs, large homolog 5 (Drosophila)
|
| Other Description |
discs large protein LP-DLG|discs large protein P-dlg|disks large homolog 5|large type of P-DLG|placenta and prostate DLG
|
| Swissprots |
Q8TDM7 Q8TDM6 Q9UE73 A6H8Y3 Q9Y4E3 Q5T1H7 Q149N1 Q5T1H8 Q86WC0 Q6DKG3
|
| Accessions |
AAL83937 CBX53876 CCQ43278 EAW54609 EAW54610 EAW54611 EAW54612 Q8TDM6 AB011155 BAA25509 AB091676 BAC65420 AK055172 AK055265 AK122931 AK314771 BAG37308 BC002915 BC013378 BC015053 BC030250 BC051757 BC073996 AAH73996 BC086867 BC117695 AAI17696 BC146794 AAI46795 BX649131 U61843 AAC61295 XM_005270276 XP_005270333 XM_006718056 XP_006718119 XM_006718057 XP_006718120 XM_006725120 XP_006725183 XM_006725122 XP_006725185 XM_006725123 XP_006725186 XM_011540341 XP_011538643 XM_011540342 XP_011538644 XM_011540343 XP_011538645 XM_011540344 XP_011538646 XM_011540345 XP_011538647 XM_011540346 XP_011538648 XM_011540347 XP_011538649 XM_011546575 XP_011544877 XM_011546576 XP_011544878 XM_011546577 XP_011544879 XM_011546578 XP_011544880 XM_011546579 XP_011544881 XM_011546580 XP_011544882 XR_945874 XR_951779 NM_004747 NP_004738
|
| Function |
May play a role at the plasma membrane in the maintenance of the structure of epithelial cells and in the transmission of extracellular signals to the membrane and cytoskeleton. {ECO:0000269|PubMed:11876824}.
|
| Subcellular Location |
Cell junction {ECO:0000269|PubMed:12657639}. Cell membrane {ECO:0000269|PubMed:12657639}; Peripheral membrane protein {ECO:0000269|PubMed:12657639}. Note=Localized at sites of cell-cell contact.
|
| Tissue Specificity |
Highly expressed in the placenta and prostate. Expressed at a lower level in the thyroid, spinal cord, trachea, adrenal gland, skeletal muscle, pancreas, heart, brain, liver and kidney. A short splice product shows more limited expression, being absent from at least the brain. {ECO:0000269|PubMed:11876824, ECO:0000269|PubMed:12657639, ECO:0000269|PubMed:9738934}.
|
