Gene Symbol |
HSC70-1
|
Entrez Gene |
831020
|
Alt Symbol |
ARABIDOPSIS THALIANA HEAT SHOCK COGNATE PROTEIN 70-1, AT-HSC70-1, HEAT SHOCK COGNATE PROTEIN 70, HEAT SHOCK PROTEIN 70-1, HSC70, HSP70-1, T22P11.90, T22P11_90, heat shock cognate protein 70-1
|
Species |
Arabidopsis thaliana
|
Gene Type |
protein-coding
|
Description |
heat shock cognate protein 70-1
|
Other Description |
-
|
Swissprots |
Q93VU6 Q9LZ52 P22953
|
Accessions |
AED90480 AED90481 CAB85987 CAW36896 CAW63862 CBC02789 CBC46282 CBD34751 P22953 AY057481 AAL09715 AY120747 AAM53305 BT002754 AAO22583 NM_001125684 NP_001119156 NM_120328 NP_195870
|
Function |
In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage (By similarity). {ECO:0000250}.
|
Subcellular Location |
Cytoplasm. Nucleus.
|
Tissue Specificity |
Expressed at a substantial level during normal growth in root, stem, leaf and flower tissues, but not in siliques. {ECO:0000269|PubMed:8049382}.
|
Top Pathways |
Endocytosis, Spliceosome, Protein processing in endoplasmic reticulum
|