Gene Symbol | CACNB3 |
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Entrez Gene | 784 |
Alt Symbol | CAB3, CACNLB3 |
Species | Human |
Gene Type | protein-coding |
Description | calcium channel, voltage-dependent, beta 3 subunit |
Other Description | voltage-dependent L-type calcium channel subunit beta-3 |
Swissprots | B7ZAK8 F5H2P6 B7Z4Q1 A8K0Z4 F8VSG3 F5GZW7 Q13913 P54284 B7Z973 |
Accessions | BAA07803 EAW58008 EAW58009 P54284 AK122911 AK289709 BAF82398 AK297639 BAH12637 AK300901 BAH13371 AK304537 BAH14209 AK316323 BAH14694 AL534844 AL537072 AL702978 BC041811 AAH41811 BI667991 CD013906 DB277524 L27584 AAA19799 U07139 AAA95958 X76555 CAA54055 X76556 CAA54056 XM_006719592 XP_006719655 XM_011538727 XP_011537029 XM_011538728 XP_011537030 XM_011538729 XP_011537031 XM_011538730 XP_011537032 NM_000725 NP_000716 NM_001206915 NP_001193844 NM_001206916 NP_001193845 NM_001206917 NP_001193846 |
Function | The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. |
Tissue Specificity | Expressed mostly in brain, smooth muscle and ovary. |
Top Pathways | MAPK signaling pathway, Cardiac muscle contraction, Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy |
L-type Ca ++ CP β3 siRNA (h) - sc-95841 from Santa Cruz Biotechnology
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L-type Ca ++ CP β3 shRNA Plasmid (h) - sc-95841-SH from Santa Cruz Biotechnology
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L-type Ca ++ CP β3 shRNA (h) Lentiviral Particles - sc-95841-V from Santa Cruz Biotechnology
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CACNB3 RNAi - H00000784-R01 from Novus Biologicals
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MISSION® esiRNA - EHU048831 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5271 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5271 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07830 from Sigma-Aldrich
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CACNB3 siRNA (Human) - CRH0549 from Cohesion Biosciences
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CACNB3 - MBS8241140 from MyBioSource
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shRNA set against Human CACNB3 (NM_000725.3) - SHH253441 from Creative biogene
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shRNA set against Human CACNB3(NM_001206916.1) - SHG131843 from Creative biogene
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shRNA set against Human CACNB3(NM_001206915.1) - SHG131873 from Creative biogene
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shRNA set against Human CACNB3(NM_000725.3) - SHG131911 from Creative biogene
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shRNA set against Human CACNB3(NM_001206915.1) - SHG131947 from Creative biogene
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shRNA set against Human CACNB3(NM_001206917.1) - SHG131959 from Creative biogene
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CACNB3 shRNA Plasmid (Human) - CHH0549 from Cohesion Biosciences
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CACNB3 miRNA 3'UTR clone - MiUTR1H-01611 from Creative biogene
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CACNB3 miRNA 3'UTR clone - MiUTR1H-01612 from Creative biogene
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CACNB3 miRNA 3'UTR clone - MiUTR1H-01613 from Creative biogene
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CACNB3 miRNA 3'UTR clone - MiUTR1H-01614 from Creative biogene
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