| Gene Symbol |
IFI27
|
| Entrez Gene |
3429
|
| Alt Symbol |
FAM14D, ISG12, ISG12A, P27
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
interferon, alpha-inducible protein 27
|
| Other Description |
2310061N23Rik|ISG12(a)|interferon alpha-induced 11.5 kDa protein|interferon alpha-inducible protein 27, mitochondrial|interferon-stimulated gene 12a protein
|
| Swissprots |
P40305 Q6IEC1 Q53YA6 Q96BK3
|
| Accessions |
CAS01779 EAW81556 EAW81557 EAW81558 P40305 AI799552 AJ294851 CAC10503 AK095039 AK097084 AK289535 BAF82224 AK312089 BAG35025 AM393107 CAL37985 AM393779 CAL38654 AU103232 AY126456 AAM95743 AY126457 AAM95744 AY126458 AAM95745 BC015492 AAH15492 BF971643 BG483267 BM756566 BM841506 BM841596 BN000227 CAE00394 BP317624 BT006781 AAP35427 BU601451 BU688913 BU928223 BX647330 CB993374 DQ893816 ABM84742 X67325 CAA47739 NM_001130080 NP_001123552 NM_001288952 NP_001275881 NM_001288954 NP_001275883 NM_001288956 NP_001275885 NM_001288957 NP_001275886 NM_001288958 NP_001275887 NM_001288959 NP_001275888 NM_001288960 NP_001275889 NM_001288995 NP_001275924 NM_005532 NP_005523
|
| Function |
Promotes cell death. Mediates IFN-induced apoptosis characterized by a rapid and robust release of cytochrome C from the mitochondria and activation of BAX and caspases 2, 3, 6, 8 and 9. {ECO:0000269|PubMed:18330707}.
|
| Subcellular Location |
Mitochondrion {ECO:0000269|PubMed:18330707}. Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
|
