Gene Symbol | CD70 |
---|---|
Entrez Gene | 970 |
Alt Symbol | CD27L, CD27LG, TNFSF7 |
Species | Human |
Gene Type | protein-coding |
Description | CD70 molecule |
Other Description | CD27 ligand|CD27-L|CD70 antigen|Ki-24 antigen|surface antigen CD70|tumor necrosis factor (ligand) superfamily, member 7|tumor necrosis factor ligand superfamily member 7 |
Swissprots | Q96J57 B4DPR8 Q53XX4 P32970 |
Accessions | ABK41892 CBX47435 CBX53853 EAW69074 EAW69075 P32970 AK298467 BAG60680 BC000725 AAH00725 BT007211 AAP35875 L08096 AAA36175 S69339 AAB30121 NM_001252 NP_001243 |
Function | Cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells. |
Subcellular Location | Membrane; Single-pass type II membrane protein. |
Top Pathways | Cytokine-cytokine receptor interaction |