Gene Symbol | BCL2L10 |
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Entrez Gene | 10017 |
Alt Symbol | BCL-B, Boo, Diva, bcl2-L-10 |
Species | Human |
Gene Type | protein-coding |
Description | BCL2-like 10 (apoptosis facilitator) |
Other Description | anti-apoptotic protein NrH|apoptosis regulator Bcl-B|bcl-2-like protein 10|death inducer binding to vBcl-2 and Apaf-1 |
Swissprots | Q3SX80 Q8TCS9 Q9HD36 Q52LQ9 |
Accessions | CAD30221 EAW77435 Q9HD36 AF285092 AAG00503 AF326964 AAK48715 BC093826 AAH93826 BC093828 AAH93828 BC104442 AAI04443 BC104443 AAI04444 BC143227 BX119239 XM_005254103 XP_005254160 NM_001306168 NP_001293097 NM_020396 NP_065129 |
Function | Promotes cell survival. Suppresses apoptosis induced by BAX but not BAK. {ECO:0000269|PubMed:11278245}. |
Subcellular Location | Mitochondrion {ECO:0000269|PubMed:11593390}. Nucleus membrane {ECO:0000269|PubMed:11593390}. |
Tissue Specificity | Widely expressed in adult tissues. Preferentially expressed in lung, liver and kidney. {ECO:0000269|PubMed:11593390}. |
Bcl-B CRISPR/Cas9 KO Plasmid (h) - sc-411404 from Santa Cruz Biotechnology
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Bcl-B HDR Plasmid (h) - sc-411404-HDR from Santa Cruz Biotechnology
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Bcl-B Double Nickase Plasmid (h) - sc-411404-NIC from Santa Cruz Biotechnology
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Bcl-B Double Nickase Plasmid (h2) - sc-411404-NIC-2 from Santa Cruz Biotechnology
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Bcl-B CRISPR Activation Plasmid (h) - sc-411404-ACT from Santa Cruz Biotechnology
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Bcl-B CRISPR Activation Plasmid (h2) - sc-411404-ACT-2 from Santa Cruz Biotechnology
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Bcl-B Lentiviral Activation Particles (h) - sc-411404-LAC from Santa Cruz Biotechnology
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Bcl-B Lentiviral Activation Particles (h2) - sc-411404-LAC-2 from Santa Cruz Biotechnology
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Bcl-B siRNA (h) - sc-90043 from Santa Cruz Biotechnology
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Bcl-B shRNA Plasmid (h) - sc-90043-SH from Santa Cruz Biotechnology
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Bcl-B shRNA (h) Lentiviral Particles - sc-90043-V from Santa Cruz Biotechnology
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BCL2L10 RNAi - H00010017-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN3908 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3908 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00582 from Sigma-Aldrich
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BCL2L10 siRNA (Human) - CRH6744 from Cohesion Biosciences
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BCL2L10 - MBS8205948 from MyBioSource
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shRNA set against Human BCL2L10 (NM_020396.2) - SHH245926 from Creative biogene
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shRNA set against Human BCL2L10(NM_020396.2) - SHG097219 from Creative biogene
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Human BCL2L10 siRNA - orb267246 from Biorbyt
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BCL2L10 shRNA Plasmid (Human) - CHH6744 from Cohesion Biosciences
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BCL2L10 miRNA 3'UTR clone - MiUTR1H-00843 from Creative biogene
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