| Gene Symbol |
HNRNPL
|
| Entrez Gene |
3191
|
| Alt Symbol |
HNRPL, P/OKcl.14, hnRNP-L
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
heterogeneous nuclear ribonucleoprotein L
|
| Other Description |
hnRNP L
|
| Swissprots |
A6ND69 P14866 Q9H3P3 A6NIT8
|
| Accessions |
EAW56826 EAW56827 EAW56828 P14866 AB044547 BAB18649 AK092828 AK094966 AK097975 AK292115 BAF84804 AK298384 BAG60620 AK301062 BAG62670 AK313652 BAG36406 AV743120 AY927544 BC069184 AAH69184 BI256815 BI461733 BM997815 BQ334900 X16135 CAA34261 XM_011526886 XP_011525188 XM_011526887 XP_011525189 XM_011526888 XP_011525190 XM_011526889 XP_011525191 XM_011526890 XP_011525192 XR_243927 NM_001005335 NP_001005335 NM_001533 NP_001524
|
| Function |
Splicing factor binding to exonic or intronic sites and acting as either an activator or repressor of exon inclusion. Exhibits a binding preference for CA-rich elements. Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes and associated with most nascent transcripts. Associates, together with APEX1, to the negative calcium responsive element (nCaRE) B2 of the APEX2 promoter. {ECO:0000269|PubMed:11809897}.
|
| Subcellular Location |
Nucleus, nucleoplasm {ECO:0000269|PubMed:17289661}. Cytoplasm {ECO:0000269|PubMed:17289661}. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
|