Gene Symbol | SH2D1B |
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Entrez Gene | 117157 |
Alt Symbol | EAT2 |
Species | Human |
Gene Type | protein-coding |
Description | SH2 domain containing 1B |
Other Description | EAT-2|EWS/FLI1-activated transcript 2|SH2 domain-containing molecule EAT2|SH2 domain-containing protein 1B |
Swissprots | Q969K9 Q8NI18 B2RBN6 Q5T0L1 O14796 |
Accessions | AAB70927 EAW90703 EAW90704 EAW90705 O14796 AF256653 AAL26000 AF403479 AAL27357 AF484964 AAM28522 AK097162 BAC04968 AK314743 BAG37283 AL709120 BC022407 AAH22407 BC066595 AAH66595 DQ891975 ABM82901 DQ895166 ABM86092 NM_053282 NP_444512 |
Function | Plays a role in controlling signal transduction through at least four receptors, CD84, SLAMF1, LY9 and CD244, expressed on the surface of professional antigen-presenting cells. |
Top Pathways | Natural killer cell mediated cytotoxicity |
EAT-2 CRISPR/Cas9 KO Plasmid (h) - sc-403780 from Santa Cruz Biotechnology
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EAT-2 HDR Plasmid (h) - sc-403780-HDR from Santa Cruz Biotechnology
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EAT-2 Double Nickase Plasmid (h) - sc-403780-NIC from Santa Cruz Biotechnology
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EAT-2 Double Nickase Plasmid (h2) - sc-403780-NIC-2 from Santa Cruz Biotechnology
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EAT-2 CRISPR Activation Plasmid (h) - sc-403780-ACT from Santa Cruz Biotechnology
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EAT-2 CRISPR Activation Plasmid (h2) - sc-403780-ACT-2 from Santa Cruz Biotechnology
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EAT-2 Lentiviral Activation Particles (h) - sc-403780-LAC from Santa Cruz Biotechnology
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EAT-2 Lentiviral Activation Particles (h2) - sc-403780-LAC-2 from Santa Cruz Biotechnology
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EAT-2 siRNA (h) - sc-42970 from Santa Cruz Biotechnology
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EAT-2 shRNA Plasmid (h) - sc-42970-SH from Santa Cruz Biotechnology
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EAT-2 shRNA (h) Lentiviral Particles - sc-42970-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU097201 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19248 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19248 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10989 from Sigma-Aldrich
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SH2D1B siRNA (Human) - CRJ4554 from Cohesion Biosciences
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SH2D1B - MBS8206109 from MyBioSource
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shRNA set against Human SH2D1B (NM_053282.4) - SHH406504 from Creative biogene
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shRNA set against Human SH2D1B(NM_053282.4) - SHR222288 from Creative biogene
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Human SH2D1B siRNA - orb275055 from Biorbyt
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SH2D1B shRNA Plasmid (Human) - CHJ4554 from Cohesion Biosciences
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SH2D1B miRNA 3'UTR clone - MiUTR1H-09355 from Creative biogene
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