JPH3

Gene Symbol JPH3
Entrez Gene 57338
Alt Symbol CAGL237, HDL2, JP-3, JP3, TNRC22
Species Human
Gene Type protein-coding
Description junctophilin 3
Other Description junctophilin type 3|junctophilin-3|trinucleotide repeat containing 22
Swissprots Q8N471 Q9HDC4 D3DUN2 Q9HDC3 Q8WXH2
Accessions AAL40941 BAB11987 EAW95386 EAW95387 Q8WXH2 AA813196 AB042636 BAB11983 AB593088 BAJ84028 AI299726 AK055486 BAG51525 AK126663 AK295518 BAG58433 AK297215 BAG59698 AW954561 BC008690 AAH08690 BC036533 AAH36533 BG205692 BI553267 BQ014355 DQ893569 ABM84495 DQ894420 ABM85346 XM_006721237 XP_006721300 NM_001271604 NP_001258533 NM_001271605 NP_001258534 NM_020655 NP_065706 NR_073379
Function Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH3 is brain- specific and appears to have an active role in certain neurons involved in motor coordination and memory.
Subcellular Location Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}. Note=Localized predominantly on the plasma membrane. The transmembrane domain is anchored in endoplasmic reticulum membrane, while the N-terminal part associates with the plasma membrane (By similarity). {ECO:0000250}.
Tissue Specificity Specifically expressed in brain. {ECO:0000269|PubMed:10891348}.

Junctophilin-3 CRISPR/Cas9 KO Plasmid (h) - sc-409301 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Junctophilin-3 HDR Plasmid (h) - sc-409301-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Junctophilin-3 Double Nickase Plasmid (h) - sc-409301-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Junctophilin-3 Double Nickase Plasmid (h2) - sc-409301-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Junctophilin-3 CRISPR Activation Plasmid (h) - sc-409301-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Junctophilin-3 CRISPR Activation Plasmid (h2) - sc-409301-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Junctophilin-3 Lentiviral Activation Particles (h) - sc-409301-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Junctophilin-3 Lentiviral Activation Particles (h2) - sc-409301-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Junctophilin-3 siRNA (h) - sc-72009 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Junctophilin-3 shRNA Plasmid (h) - sc-72009-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Junctophilin-3 shRNA (h) Lentiviral Particles - sc-72009-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU060401 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10878 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10878 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09406 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr09406

JPH3 siRNA (Human) - CRJ1420 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

JPH3, siRNA - MBS8218652 from MyBioSource

Category siRNA
Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human JPH3 (NM_020655.3) - SHH322191 from Creative biogene

Category siRNA
Species Reactivities Human

Human JPH3 siRNA - orb271921 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

JPH3 shRNA Plasmid (Human) - CHJ1420 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

JPH3 miRNA 3'UTR clone - MiUTR3H-07523 from Creative biogene

Species Reactivities Human
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