Gene Symbol | C6 |
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Entrez Gene | 729 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | complement component 6 |
Other Description | complement component C6 |
Swissprots | P13671 |
Accessions | CAA50994 EAW56012 EAW56013 P13671 AB126592 BAD02321 AK292509 BAF85198 AK313673 BC035723 AAH35723 BJ993387 DB066614 DB184605 DQ891257 ABM82183 DQ894443 ABM85369 J04506 AAB59433 J05024 AAA59668 J05063 J05064 AAA51860 XM_005248357 XP_005248414 XM_006714496 XP_006714559 XM_011514114 XP_011512416 XM_011514115 XP_011512417 XM_011514116 XP_011512418 XM_011514117 XP_011512419 XM_011514118 XP_011512420 XM_011514119 XP_011512421 XM_011514120 XP_011512422 XM_011514121 XP_011512423 NM_000065 NP_000056 NM_001115131 NP_001108603 |
Function | Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. |
Subcellular Location | Secreted. |
Top Pathways | Complement and coagulation cascades, Systemic lupus erythematosus, Prion diseases |
C6 CRISPR/Cas9 KO Plasmid (h) - sc-404236 from Santa Cruz Biotechnology
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C6 HDR Plasmid (h) - sc-404236-HDR from Santa Cruz Biotechnology
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C6 Double Nickase Plasmid (h) - sc-404236-NIC from Santa Cruz Biotechnology
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C6 Double Nickase Plasmid (h2) - sc-404236-NIC-2 from Santa Cruz Biotechnology
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C6 CRISPR Activation Plasmid (h) - sc-404236-ACT from Santa Cruz Biotechnology
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C6 CRISPR Activation Plasmid (h2) - sc-404236-ACT-2 from Santa Cruz Biotechnology
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C6 Lentiviral Activation Particles (h) - sc-404236-LAC from Santa Cruz Biotechnology
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C6 Lentiviral Activation Particles (h2) - sc-404236-LAC-2 from Santa Cruz Biotechnology
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C6 siRNA (h) - sc-72769 from Santa Cruz Biotechnology
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C6 shRNA Plasmid (h) - sc-72769-SH from Santa Cruz Biotechnology
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C6 shRNA (h) Lentiviral Particles - sc-72769-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU133031 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5005 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5005 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04795 from Sigma-Aldrich
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C6 siRNA (Human) - CRH0506 from Cohesion Biosciences
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C6 - MBS8211898 from MyBioSource
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C6 shRNA Plasmid (Human) - CHH0506 from Cohesion Biosciences
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C6 miRNA 3'UTR clone - MiUTR3H-02459 from Creative biogene
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C6 miRNA 3'UTR clone - MiUTR3H-02460 from Creative biogene
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