Gene Symbol | EGFLAM |
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Entrez Gene | 133584 |
Alt Symbol | AGRINL, AGRNL, PIKA |
Species | Human |
Gene Type | protein-coding |
Description | EGF-like, fibronectin type III and laminin G domains |
Other Description | EGF-like, fibronectin type-III and laminin G-like domain-containing protein|agrin-like protein|pikachurin |
Swissprots | Q8N7Y0 Q8NAL2 Q5U643 A8K6D7 Q8N124 Q6P3V1 Q63HQ2 Q8N197 Q8N8N5 |
Accessions | EAW55966 EAW55967 EAW55968 EAW55969 EAW55970 Q63HQ2 AK092479 BAC03900 AK092994 BAC04013 AK096474 BAC04800 AK097549 BAC05096 AK291602 BAF84291 AL832269 AL833357 BC031251 AAH31251 BC033177 AAH33177 BC033188 AAH33188 BC063822 AAH63822 BM928177 BX647551 CAH56137 DN995271 NM_182799 NM_001205301 NP_001192230 NM_152403 NP_689616 NM_182798 NP_877950 NM_182801 NP_877953 |
Function | Involved in both the retinal photoreceptor ribbon synapse formation and physiological functions of visual perception. Necessary for proper bipolar dendritic tip apposition to the photoreceptor ribbon synapse. Promotes matrix assembly and cell adhesiveness (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000250}. Cell junction, synapse {ECO:0000250}. Note=Detected in the synaptic cleft of the ribbon synapse around the postsynaptic terminals of bipolar cells. Colocalizes with BSN, CTBP2 and DAG1 in photoreceptor synaptic terminals (By similarity). {ECO:0000250}. |
EGFLAM CRISPR/Cas9 KO Plasmid (h) - sc-417217 from Santa Cruz Biotechnology
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EGFLAM HDR Plasmid (h) - sc-417217-HDR from Santa Cruz Biotechnology
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EGFLAM Double Nickase Plasmid (h) - sc-417217-NIC from Santa Cruz Biotechnology
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EGFLAM Double Nickase Plasmid (h2) - sc-417217-NIC-2 from Santa Cruz Biotechnology
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EGFLAM CRISPR Activation Plasmid (h) - sc-417217-ACT from Santa Cruz Biotechnology
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EGFLAM CRISPR Activation Plasmid (h2) - sc-417217-ACT-2 from Santa Cruz Biotechnology
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EGFLAM Lentiviral Activation Particles (h) - sc-417217-LAC from Santa Cruz Biotechnology
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EGFLAM Lentiviral Activation Particles (h2) - sc-417217-LAC-2 from Santa Cruz Biotechnology
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EGFLAM siRNA (h) - sc-91774 from Santa Cruz Biotechnology
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EGFLAM shRNA Plasmid (h) - sc-91774-SH from Santa Cruz Biotechnology
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EGFLAM shRNA (h) Lentiviral Particles - sc-91774-V from Santa Cruz Biotechnology
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EGFLAM RNAi - H00133584-R03 from Novus Biologicals
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EGFLAM RNAi - H00133584-R01 from Novus Biologicals
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EGFLAM RNAi - H00133584-R02 from Novus Biologicals
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MISSION® esiRNA - EHU082721 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7712 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7712 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09584 from Sigma-Aldrich
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EGFLAM siRNA (Human) - CRJ5120 from Cohesion Biosciences
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EGFLAM RNAi - H00133584-R04 from Novus Biologicals
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EGFLAM - MBS8227056 from MyBioSource
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shRNA set against Human EGFLAM (NM_182801.2) - SHH283841 from Creative biogene
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Human EGFLAM siRNA - orb275621 from Biorbyt
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EGFLAM shRNA Plasmid (Human) - CHJ5120 from Cohesion Biosciences
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EGFLAM miRNA 3'UTR clone - MiUTR3H-14718 from Creative biogene
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