Gene Symbol | PRKG2 |
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Entrez Gene | 5593 |
Alt Symbol | PRKGR2, cGK2, cGKII |
Species | Human |
Gene Type | protein-coding |
Description | protein kinase, cGMP-dependent, type II |
Other Description | cGMP-dependent protein kinase 2|cGMP-dependent protein kinase II |
Swissprots | O60916 E7EPE6 Q13237 O00125 B4DMX3 |
Accessions | CAA76073 EAX05867 Q13237 AK296979 BAG59521 AK297673 BAG60035 AK316140 BAH14511 BC111597 AAI11598 BF508892 D70899 BAA18934 DA462272 DA569289 DB455792 DC348270 X94612 CAA64318 XM_005263126 XP_005263183 XM_006714266 XP_006714329 XM_011532114 XP_011530416 XM_011532115 XP_011530417 XM_011532116 XP_011530418 NM_001282480 NP_001269409 NM_001282481 NP_001269410 NM_001282482 NP_001269411 NM_001282483 NP_001269412 NM_001282485 NP_001269414 NM_006259 NP_006250 |
Subcellular Location | Apical cell membrane {ECO:0000269|PubMed:8636133}; Lipid-anchor {ECO:0000269|PubMed:8636133}. |
Tissue Specificity | Highly concentrated in brain, lung and intestinal mucosa. |
Top Pathways | Gap junction, Long-term depression, Olfactory transduction, Salivary secretion, Circadian entrainment |
cGKII CRISPR/Cas9 KO Plasmid (h) - sc-404138 from Santa Cruz Biotechnology
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cGKII HDR Plasmid (h) - sc-404138-HDR from Santa Cruz Biotechnology
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cGKII Double Nickase Plasmid (h) - sc-404138-NIC from Santa Cruz Biotechnology
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cGKII Double Nickase Plasmid (h2) - sc-404138-NIC-2 from Santa Cruz Biotechnology
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cGKII CRISPR Activation Plasmid (h) - sc-404138-ACT from Santa Cruz Biotechnology
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cGKII CRISPR Activation Plasmid (h2) - sc-404138-ACT-2 from Santa Cruz Biotechnology
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cGKII Lentiviral Activation Particles (h) - sc-404138-LAC from Santa Cruz Biotechnology
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cGKII Lentiviral Activation Particles (h2) - sc-404138-LAC-2 from Santa Cruz Biotechnology
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cGKII siRNA (h) - sc-38974 from Santa Cruz Biotechnology
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cGKII shRNA Plasmid (h) - sc-38974-SH from Santa Cruz Biotechnology
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cGKII shRNA (h) Lentiviral Particles - sc-38974-V from Santa Cruz Biotechnology
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cGK2/PRKG2 RNAi - H00005593-R02 from Novus Biologicals
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MISSION® esiRNA - EHU160001 from Sigma-Aldrich
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MISSION® siRNA - SIHK1868 from Sigma-Aldrich
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MISSION® siRNA - SIHK1867 from Sigma-Aldrich
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MISSION® siRNA - SIHK1869 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17428 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17428 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07604 from Sigma-Aldrich
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PRKG2 siRNA (Human) - CRH3763 from Cohesion Biosciences
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shRNA set against Human PRKG2 (NM_006259.1) - SHH382972 from Creative biogene
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shRNA set against Human PRKG2(NM_006259.1) - SHR140838 from Creative biogene
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PRKG2 shRNA Plasmid (Human) - CHH3763 from Cohesion Biosciences
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PRKG2 miRNA 3'UTR clone - MiUTR1H-08289 from Creative biogene
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