| Gene Symbol |
GOT2
|
| Entrez Gene |
100348732
|
| Alt Symbol |
FABP-1, FABPpm, mAspAT
|
| Species |
Rabbit
|
| Gene Type |
protein-coding
|
| Description |
glutamic-oxaloacetic transaminase 2, mitochondrial
|
| Other Description |
Aspartate aminotransferase, mitochondrial|Fatty acid-binding protein|Glutamate oxaloacetate transaminase 2|Kynurenine aminotransferase 4|Kynurenine aminotransferase IV|Kynurenine--oxoglutarate transaminase 4|Kynurenine--oxoglutarate transaminase IV|Plasma membrane-associated fatty acid-binding protein|Transaminase A
|
| Swissprots |
G1SKL2 P12345
|
| Accessions |
P12345 XM_002711551 XP_002711597
|
| Function |
Catalyzes the irreversible transamination of the L- tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Mitochondrion matrix {ECO:0000250}. Cell membrane {ECO:0000250}.
|
| Top Pathways |
Fat digestion and absorption, Cysteine and methionine metabolism, Tyrosine metabolism, 2-Oxocarboxylic acid metabolism, Carbon metabolism
|