Gene Symbol |
MGAT5
|
Entrez Gene |
4249
|
Alt Symbol |
GNT-V, GNT-VA
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
|
Other Description |
N-acetylglucosaminyl-transferase V|alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A|alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase|glcNAc-T V|mannoside acetylglucosaminyltransferase 5
|
Swissprots |
Q09328 D3DP70
|
Accessions |
AAB81939 AAX93248 AAY14747 AAY14791 EAX11657 EAX11658 Q09328 AF055029 AF113921 AAD22449 AK056461 AK125207 BC041917 BC156313 AAI56314 BC157048 AAI57049 BU191961 BX647087 D17716 BAA04570 DB223638 DB237089 XM_005263668 XP_005263725 XM_005263669 XP_005263726 XM_005263670 XP_005263727 XM_006712534 XP_006712597 XM_006712535 XP_006712598 XM_011511199 XP_011509501 XM_011511200 XP_011509502 XM_011511201 XP_011509503 XM_011511202 XP_011509504 XM_011511203 XP_011509505 XM_011511204 XP_011509506 NM_002410 NP_002401
|
Function |
Catalyzes the addition of N-acetylglucosamine in beta 1- 6 linkage to the alpha-linked mannose of biantennary N-linked oligosaccharides. It is one of the most important enzymes involved in the regulation of the biosynthesis of glycoprotein oligosaccharides.
|
Subcellular Location |
Golgi apparatus membrane; Single-pass type II membrane protein.
|
Top Pathways |
N-Glycan biosynthesis
|