Gene Symbol | UNC13C |
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Entrez Gene | 440279 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | unc-13 homolog C (C. elegans) |
Other Description | Munc13-3|protein unc-13 homolog C|unc-13-like 3 |
Swissprots | Q8ND48 Q0P613 Q96NP3 Q8NB66 |
Accessions | CCQ43068 Q8NB66 AK054981 BAB70836 AK091491 BAC03675 AK293996 BAG57359 AL834407 CAD39069 BC036420 BC039494 BC040740 AAH40740 BC156424 AAI56425 XM_005254394 XP_005254451 XM_005254395 XP_005254452 NM_001080534 NP_001074003 |
Function | May play a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. May be involved in the regulation of synaptic transmission at parallel fiber - Purkinje cell synapses (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cell junction, synapse, presynaptic cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Localized to presynaptic structures. {ECO:0000250}. |
Tissue Specificity | Exclusively expressed in brain. |
Top Pathways | Synaptic vesicle cycle |
Munc13-3 CRISPR/Cas9 KO Plasmid (h) - sc-408694 from Santa Cruz Biotechnology
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Munc13-3 HDR Plasmid (h) - sc-408694-HDR from Santa Cruz Biotechnology
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Munc13-3 Double Nickase Plasmid (h) - sc-408694-NIC from Santa Cruz Biotechnology
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Munc13-3 Double Nickase Plasmid (h2) - sc-408694-NIC-2 from Santa Cruz Biotechnology
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Munc13-3 CRISPR Activation Plasmid (h) - sc-408694-ACT from Santa Cruz Biotechnology
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Munc13-3 CRISPR Activation Plasmid (h2) - sc-408694-ACT-2 from Santa Cruz Biotechnology
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Munc13-3 Lentiviral Activation Particles (h) - sc-408694-LAC from Santa Cruz Biotechnology
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Munc13-3 Lentiviral Activation Particles (h2) - sc-408694-LAC-2 from Santa Cruz Biotechnology
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Munc13-3 siRNA (h) - sc-42024 from Santa Cruz Biotechnology
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Munc13-3 shRNA Plasmid (h) - sc-42024-SH from Santa Cruz Biotechnology
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Munc13-3 shRNA (h) Lentiviral Particles - sc-42024-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU077021 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22495 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22495 from Sigma-Aldrich
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UNC13C siRNA (Human) - CRJ8245 from Cohesion Biosciences
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UNC13C - MBS8220973 from MyBioSource
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shRNA set against Human Unc13c (NM_001080534.1) - SHH440500 from Creative biogene
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shRNA set against Human UNC13C(NM_001080534.1) - SHL114624 from Creative biogene
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Human UNC13C siRNA - orb278746 from Biorbyt
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UNC13C shRNA Plasmid (Human) - CHJ8245 from Cohesion Biosciences
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UNC13C miRNA 3'UTR clone - MiUTR1H-11010 from Creative biogene
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