| Gene Symbol |
UXS1
|
| Entrez Gene |
80146
|
| Alt Symbol |
SDR6E1, UGD
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
UDP-glucuronate decarboxylase 1
|
| Other Description |
UDP-glucuronic acid decarboxylase 1|UXS-1|short chain dehydrogenase/reductase family 6E, member 12
|
| Swissprots |
Q8NBX3 Q8NBZ7 Q9H5C2
|
| Accessions |
AAY15085 CAF86373 CAF86438 EAX01747 EAX01748 EAX01749 EAX01750 Q8NBZ7 AI217133 AK027244 BAB15705 AK056022 AK057242 AK075120 BAC11415 AK075170 BAC11448 AK122696 BAG53673 AK225592 AK290668 BAF83357 AK304872 BAG65609 AL834439 CAD39099 AY147934 AAN39844 AY358541 AAQ88905 BC009819 AAH09819 BI550591 BI825770 BM472113 BX366726 CF242897 DB379311 DQ893252 ABM84178 DQ896581 ABM87580 XM_006712775 XP_006712838 XM_011511902 XP_011510204 XM_011511903 XP_011510205 XM_011511904 XP_011510206 NM_001253875 NP_001240804 NM_001253876 NP_001240805 NM_025076 NP_079352 NR_045607
|
| Function |
Catalyzes the NAD-dependent decarboxylation of UDP- glucuronic acid to UDP-xylose. Necessary for the biosynthesis of the core tetrasaccharide in glycosaminoglycan biosynthesis.
|
| Subcellular Location |
Golgi apparatus, Golgi stack membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
|
| Top Pathways |
Amino sugar and nucleotide sugar metabolism, Starch and sucrose metabolism
|
![Western Blot: UXS1 Overexpression Lysate (Adult Normal) [NBL1-17685] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for UXS1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/9161_UXS1%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-17685-img0002.jpg)