| Gene Symbol |
Acaca
|
| Entrez Gene |
107476
|
| Alt Symbol |
A530025K05Rik, Acac, Acc1, Gm738
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
acetyl-Coenzyme A carboxylase alpha
|
| Other Description |
ACC-alpha|acaca|acetyl-CoA carboxylase 1|acetyl-CoA carboxylase 265
|
| Swissprots |
Q6PHL9 Q5SWU8 Q91VC8 Q925C4 Q6JIZ1 Q5SWU9 Q705X8 A2A6H4 Q925C5 Q705X9 Q5SWU7 Q5SWU6
|
| Accessions |
CAF02252 EDL15735 Q5SWU9 AF289714 AAG01858 AF374167 AAK57389 AF374168 AAK57390 AF374169 AAK57391 AF374170 AAK57392 AJ619664 CAF02251 AK040794 AK040962 AK047036 AK132628 AK144072 AY451393 AAS13685 BC023946 BC042725 BC049923 BC056500 AAH56500 BC064472 BC156144 AAI56145 BC156982 AAI56983 BY726813 CF745722 CN538919 CN705188 XM_006531953 XP_006532016 XM_006531954 XP_006532017 XM_006531955 XP_006532018 XM_006531956 XP_006532019 XM_006531957 XP_006532020 XM_006531958 XP_006532021 XM_011248666 XP_011246968 XM_011248667 XP_011246969 NM_133360 NP_579938
|
| Function |
Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. {ECO:0000250|UniProtKB:Q13085}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:12360400, ECO:0000269|PubMed:20952656}.
|
| Top Pathways |
Insulin signaling pathway, AMPK signaling pathway, Glucagon signaling pathway, Fatty acid biosynthesis, Pyruvate metabolism
|