NEUROD1

Gene Symbol	NEUROD1
Entrez Gene	4760
Alt Symbol	BETA2, BHF-1, MODY6, NEUROD, bHLHa3
Species	Human
Gene Type	protein-coding
Description	neuronal differentiation 1
Other Description	basic helix-loop-helix transcription factor|beta-cell E-box transactivator 2|class A basic helix-loop-helix protein 3|neurogenic differentiation factor 1|neurogenic helix-loop-helix protein NEUROD
Swissprots	Q13340 Q9UEC8 Q96TH0 Q99455 Q13562 F1T0E1 O00343 B2R9I8 Q5U095
Accessions	AAA93480 AAC83145 AAY24267 BAA36519 BAA76603 BAA87605 EAX10983 Q13562 AB593068 BAJ84015 AB593069 BAJ84016 AB593070 BAJ84017 AB593071 BAJ84018 AK313799 BAG36535 BC009046 AAH09046 BM505034 BT019731 AAV38536 D82347 BAA11558 DA486317 DB472071 DN949274 DQ891560 ABM82486 DQ894747 ABM85673 GQ904713 ADM86143 U36472 AAA79702 U80578 AAC51318 NM_002500 NP_002491
Function	Acts as a transcriptional activator: mediates transcriptional activation by binding to E box-containing promoter consensus core sequences 5'-CANNTG-3'. Associates with the p300/CBP transcription coactivator complex to stimulate transcription of the secretin gene as well as the gene encoding the cyclin-dependent kinase inhibitor CDKN1A. Contributes to the regulation of several cell differentiation pathways, like those that promote the formation of early retinal ganglion cells, inner ear sensory neurons, granule cells forming either the cerebellum or the dentate gyrus cell layer of the hippocampus, endocrine islet cells of the pancreas and enteroendocrine cells of the small intestine. Together with PAX6 or SIX3, is required for the regulation of amacrine cell fate specification. Also required for dendrite morphogenesis and maintenance in the cerebellar cortex. Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis (By si
Subcellular Location	Cytoplasm {ECO:0000250}. Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981, ECO:0000269|PubMed:14752053}. Note=In pancreatic islet cells, shuttles to the nucleus in response to glucose stimulation (By similarity). Colocalizes with NR0B2 in the nucleus. {ECO:0000250}.
Top Pathways	Maturity onset diabetes of the young

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NeuroD1 full length protein - ab152566 from Abcam Category Protein Source Wheat germ Species Human

Human NeuroD1 peptide - ab17100 from Abcam Category Peptide

Human NeuroD1 protein fragment - ab152567 from Abcam Category Protein Source Wheat germ Species Human

NEUROD1 Antibody Blocking Peptide - LS-E6813 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NEUROD1 Antibody Blocking Peptide - LS-E6814 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NEUROD1 Antibody Blocking Peptide - LS-E13706 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NeuroD1 Partial Recombinant Protein - H00004760-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human NeuroD1 Protein - H00004760-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

NeuroD1 Peptide - P0818 from Novus Biologicals Category Peptide Species Human

NeuroD1 Peptide - P0817 from Novus Biologicals Category Peptide Species Human

NeuroD1-Antibody-N-term-Blocking-Peptide - BP2021a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

NeuroD1-Antibody-C-term-Blocking-Peptide - BP2021b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GABA A Receptor beta 2 blocking peptide - GTX47564-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat, Bovine

NEUROD1 - H00004760-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

NEUROD1 - H00004760-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

NEUROD1 - H00004760-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

NEUROD1 fusion protein - Ag2713 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human NEUROD1, GST-tagged - NEUROD1-1268H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human NEUROD1 - NEUROD1-555H from Creative Biomart Category Protein Source Mammalian Cells Species Human

Recombinant Human Neurogenic differentiation factor 1(NEUROD1) - CSB-YP615700HU CSB-EP615700HU CSB-BP615700HU CSB-MP615700HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

NEUROD1 - TP301987 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

NeuroD1, Peptide - MBS658196 from MyBioSource Category Peptide Prices $290.00 Sizes 1 mg Species Human, Rodent

NeuroD1, Peptide - MBS659842 from MyBioSource Category Peptide Prices $290.00 Sizes 1 mg Source Synthetic peptide Species Human, Rodent

NeuroD1 Recombinant Protein Antigen - NBP1-88661PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

NEUROD1 Peptide, Human - M34GP10314H from Creative Peptides Category Peptide Source Synthetic. Species Human

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