| Gene Symbol | LAMP5 |
|---|---|
| Entrez Gene | 24141 |
| Alt Symbol | BAD-LAMP, BADLAMP, C20orf103, LAMP-5, UNC-43 |
| Species | Human |
| Gene Type | protein-coding |
| Description | lysosomal-associated membrane protein family, member 5 |
| Other Description | LAMP family protein C20orf103|brain and dendritic cell associated LAMP|brain and dendritic cell-associated LAMP|brain-associated LAMP-like protein|lysosome-associated membrane glycoprotein 5|lysosome-associated membrane protein 5 |
| Swissprots | B4DHZ7 B7Z9Z9 Q9UJQ1 |
| Accessions | CAJ42717 CAT03711 CAT03723 CAV33173 EAX10361 EAX10362 Q9UJQ1 AK295336 BAG58309 AK316114 BAH14485 AL121740 CAB57330 BC050727 AAH50727 BG707942 BI602543 XM_011529206 XP_011527508 NM_001199897 NP_001186826 NM_012261 NP_036393 |
| Subcellular Location | Cell membrane {ECO:0000269|PubMed:21642595}; Single-pass type I membrane protein {ECO:0000269|PubMed:21642595}. Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000269|PubMed:21642595}; Single-pass type I membrane protein {ECO:0000269|PubMed:21642595}. Endosome membrane {ECO:0000269|PubMed:21642595}; Single-pass type I membrane protein {ECO:0000269|PubMed:21642595}. Cytoplasmic vesicle {ECO:0000250}. Cell projection, dendrite {ECO:0000250}. Cell projection, growth cone membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Early endosome membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Recycling endosome {ECO:0000250}. Note=Localized mostly in cytoplasmic vesicles of neuronal cell body. Recycles from the vesicles of the endocytic recycling compartment (ERC) to the plasma membrane (By similarity). Colocalizes with UNC93B1 in large endosomal intracellular vesicles. Accumulates in the endoplasmic reticulum- Golgi intermediat |
| Tissue Specificity | Expressed in plasmocytoid dendritic cells. Expressed in suprabasal skin keratinocytes and squamous cells (at protein level). Expressed in the brain and weakly in spleen and skin. Expressed in plasmocytoid dendritic cells. {ECO:0000269|PubMed:21642595}. |
C20orf103 CRISPR/Cas9 KO Plasmid (h) - sc-411790 from Santa Cruz Biotechnology
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C20orf103 HDR Plasmid (h) - sc-411790-HDR from Santa Cruz Biotechnology
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C20orf103 Double Nickase Plasmid (h) - sc-411790-NIC from Santa Cruz Biotechnology
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C20orf103 Double Nickase Plasmid (h2) - sc-411790-NIC-2 from Santa Cruz Biotechnology
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C20orf103 CRISPR Activation Plasmid (h) - sc-411790-ACT from Santa Cruz Biotechnology
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C20orf103 CRISPR Activation Plasmid (h2) - sc-411790-ACT-2 from Santa Cruz Biotechnology
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C20orf103 Lentiviral Activation Particles (h) - sc-411790-LAC from Santa Cruz Biotechnology
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C20orf103 Lentiviral Activation Particles (h2) - sc-411790-LAC-2 from Santa Cruz Biotechnology
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C20orf103 siRNA (h) - sc-72692 from Santa Cruz Biotechnology
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C20orf103 shRNA Plasmid (h) - sc-72692-SH from Santa Cruz Biotechnology
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C20orf103 shRNA (h) Lentiviral Particles - sc-72692-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU053641 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN4704 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4704 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05738 from Sigma-Aldrich
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LAMP5 siRNA (Human) - CRH8470 from Cohesion Biosciences
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shRNA set against Human C20orf103 (NM_012261.3) - SHH250925 from Creative biogene
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Human LAMP5 siRNA - orb268972 from Biorbyt
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LAMP5 shRNA Plasmid (Human) - CHH8470 from Cohesion Biosciences
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LAMP5 miRNA 3'UTR clone - MiUTR3H-13334 from Creative biogene
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