Gene Symbol | SRP14 |
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Entrez Gene | 6727 |
Alt Symbol | ALURBP |
Species | Human |
Gene Type | protein-coding |
Description | signal recognition particle 14kDa (homologous Alu RNA binding protein) |
Other Description | 18 kDa Alu RNA-binding protein|signal recognition particle 14 kDa protein |
Swissprots | Q6B0K5 B5BUF5 P37108 Q96Q14 |
Accessions | EAW92390 EAW92391 P37108 AB061546 BAB69067 AB451391 BAG70205 BC035495 AAH35495 BC051006 BC071716 AAH71716 BC100031 AAI00032 CV575824 HQ447734 ADQ32219 U07857 AAA59066 X73459 CAA51838 NM_003134 NP_003125 NR_104021 |
Function | Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding. |
Subcellular Location | Cytoplasm. |
Top Pathways | Protein export |
SRP14 CRISPR/Cas9 KO Plasmid (h) - sc-417323 from Santa Cruz Biotechnology
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SRP14 HDR Plasmid (h) - sc-417323-HDR from Santa Cruz Biotechnology
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SRP14 Double Nickase Plasmid (h) - sc-417323-NIC from Santa Cruz Biotechnology
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SRP14 Double Nickase Plasmid (h2) - sc-417323-NIC-2 from Santa Cruz Biotechnology
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SRP14 CRISPR Activation Plasmid (h) - sc-417323-ACT from Santa Cruz Biotechnology
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SRP14 CRISPR Activation Plasmid (h2) - sc-417323-ACT-2 from Santa Cruz Biotechnology
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SRP14 Lentiviral Activation Particles (h) - sc-417323-LAC from Santa Cruz Biotechnology
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SRP14 Lentiviral Activation Particles (h2) - sc-417323-LAC-2 from Santa Cruz Biotechnology
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SRP14 siRNA (h) - sc-41361 from Santa Cruz Biotechnology
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SRP14 shRNA Plasmid (h) - sc-41361-SH from Santa Cruz Biotechnology
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SRP14 shRNA (h) Lentiviral Particles - sc-41361-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU024701 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20578 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20578 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05128 from Sigma-Aldrich
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SRP14 siRNA (Human) - CRH4594 from Cohesion Biosciences
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SRP14 RNAi - H00006727-R01 from Novus Biologicals
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SRP14 - MBS8203269 from MyBioSource
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shRNA set against Human SRP14(NM_003134.4) - SHL034694 from Creative biogene
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Human SRP14 siRNA - orb265096 from Biorbyt
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SRP14 shRNA Plasmid (Human) - CHH4594 from Cohesion Biosciences
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SRP14 miRNA 3'UTR clone - MiUTR1H-09909 from Creative biogene
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