Gene Symbol | FMO1 |
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Entrez Gene | 2326 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | flavin containing monooxygenase 1 |
Other Description | FMO 1|Flavin-containing monooxygenase 1 (fetal liver)|dimethylaniline monooxygenase [N-oxide-forming] 1|dimethylaniline oxidase 1|fetal hepatic flavin-containing monooxygenase 1 |
Swissprots | A8K248 Q9UJC2 Q5QPT2 Q01740 B7Z3P4 |
Accessions | AAW56076 CCQ43165 EAW90892 EAW90893 EAW90894 EAW90895 Q01740 AK097039 AK290113 BAF82802 AK296198 BAH12280 AK315100 BAG37562 BC047129 AAH47129 BE465459 DA537896 DA750161 HQ257928 ADR82682 M64082 AAA52457 XM_005245037 XP_005245094 XM_005245038 XP_005245095 XM_006711241 XP_006711304 XM_006711242 XP_006711305 NM_001282692 NP_001269621 NM_001282693 NP_001269622 NM_001282694 NP_001269623 NM_002021 NP_002012 |
Function | This protein is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides. Form I catalyzes the N-oxygenation of secondary and tertiary amines. |
Subcellular Location | Microsome membrane. Endoplasmic reticulum membrane. |
Tissue Specificity | Expressed mainly in fetal liver, adult kidney and, to a lesser extent, the intestine. |
Top Pathways | Drug metabolism - cytochrome P450 |
FMO1 CRISPR/Cas9 KO Plasmid (h) - sc-404620 from Santa Cruz Biotechnology
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FMO1 HDR Plasmid (h) - sc-404620-HDR from Santa Cruz Biotechnology
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FMO1 Double Nickase Plasmid (h) - sc-404620-NIC from Santa Cruz Biotechnology
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FMO1 Double Nickase Plasmid (h2) - sc-404620-NIC-2 from Santa Cruz Biotechnology
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FMO1 CRISPR Activation Plasmid (h) - sc-404620-ACT from Santa Cruz Biotechnology
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FMO1 CRISPR Activation Plasmid (h2) - sc-404620-ACT-2 from Santa Cruz Biotechnology
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FMO1 Lentiviral Activation Particles (h) - sc-404620-LAC from Santa Cruz Biotechnology
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FMO1 Lentiviral Activation Particles (h2) - sc-404620-LAC-2 from Santa Cruz Biotechnology
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FMO1 siRNA (h) - sc-75041 from Santa Cruz Biotechnology
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FMO1 shRNA Plasmid (h) - sc-75041-SH from Santa Cruz Biotechnology
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FMO1 shRNA (h) Lentiviral Particles - sc-75041-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU059621 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8840 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8840 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03782 from Sigma-Aldrich
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FMO1 siRNA (Human) - CRH1629 from Cohesion Biosciences
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FMO1 - MBS8240677 from MyBioSource
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shRNA set against Human FMO1 (NM_002021.1) - SHH295893 from Creative biogene
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shRNA set against Human FMO1(NM_002021.1) - SHH063953 from Creative biogene
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Human FMO1 siRNA - orb262131 from Biorbyt
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FMO1 shRNA Plasmid (Human) - CHH1629 from Cohesion Biosciences
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FMO1 miRNA 3'UTR clone - MiUTR1H-03781 from Creative biogene
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