| Gene Symbol | Unc45b |
|---|---|
| Entrez Gene | 217012 |
| Alt Symbol | AA445617, Cmya4, D230041A13Rik, Unc45 |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | unc-45 homolog B (C. elegans) |
| Other Description | UNC-45B|cardiomyopathy associated 4|protein unc-45 homolog B|striated muscle UNC45 |
| Swissprots | Q8CGY6 Q8BHC5 Q8BWK3 Q5XG72 |
| Accessions | EDL15684 Q8CGY6 AF539793 AAO13383 AK052294 BAC34921 AK081821 BAC38342 AK084418 BAC39178 AK168968 AK169274 BC084585 AAH84585 BY133112 NM_178680 NP_848795 |
| Function | Acts as a co-chaperone for HSP90 and is required for proper folding of the myosin motor domain. Plays a role in sarcomere formation during muscle cell development. {ECO:0000269|PubMed:12356907, ECO:0000269|PubMed:18326487, ECO:0000269|PubMed:18478096}. |
| Subcellular Location | Cytoplasm, cytosol {ECO:0000269|PubMed:18478096}. |
| Tissue Specificity | Highly expressed in adult skeletal muscle and heart. Detected at intermediate levels in lung. Highly expressed in embryonic heart. {ECO:0000269|PubMed:12356907}. |