Gene Symbol | FAM126A |
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Entrez Gene | 84668 |
Alt Symbol | DRCTNNB1A, HCC, HLD5, HYCC1 |
Species | Human |
Gene Type | protein-coding |
Description | family with sequence similarity 126, member A |
Other Description | down regulated by Ctnnb1, a|down-regulated by CTNNB1 protein A|hyccin |
Swissprots | Q96NQ6 Q6N010 Q7LDZ4 A4D145 Q75MR4 Q96MX1 Q9BYI3 |
Accessions | AAS01991 AAS07519 EAL24262 EAW93767 EAW93768 Q9BYI3 AA811006 AB030241 BAB39849 AK054887 BAB70823 AK056319 BAB71148 AK057686 AK297399 BAG59839 AL833296 BC018710 AAH18710 BX640757 CAE45864 DB099987 DQ891698 ABM82624 DQ895341 ABM86267 XM_005249894 XP_005249951 XM_005249895 XP_005249952 XM_006715799 XP_006715862 XM_011515589 XP_011513891 XM_011515590 XP_011513892 NM_032581 NP_115970 |
Function | May have a role in the beta-catenin/Lef signaling pathway. May have a role in the process of myelination of the central and peripheral nervous system. {ECO:0000269|PubMed:16951682}. |
Subcellular Location | Cytoplasm. Membrane. Note=According to PubMed:10910037, it is mainly cytoplasmic while according to PubMed:16951682, it is a membrane protein. |
Tissue Specificity | Widely expressed. Highest levels in heart, brain, placenta, spleen and testis. {ECO:0000269|PubMed:10910037}. |
hyccin CRISPR/Cas9 KO Plasmid (h) - sc-405671 from Santa Cruz Biotechnology
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hyccin HDR Plasmid (h) - sc-405671-HDR from Santa Cruz Biotechnology
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hyccin Double Nickase Plasmid (h) - sc-405671-NIC from Santa Cruz Biotechnology
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hyccin Double Nickase Plasmid (h2) - sc-405671-NIC-2 from Santa Cruz Biotechnology
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hyccin CRISPR Activation Plasmid (h) - sc-405671-ACT from Santa Cruz Biotechnology
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hyccin CRISPR Activation Plasmid (h2) - sc-405671-ACT-2 from Santa Cruz Biotechnology
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hyccin Lentiviral Activation Particles (h) - sc-405671-LAC from Santa Cruz Biotechnology
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hyccin Lentiviral Activation Particles (h2) - sc-405671-LAC-2 from Santa Cruz Biotechnology
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hyccin siRNA (h) - sc-89596 from Santa Cruz Biotechnology
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hyccin shRNA Plasmid (h) - sc-89596-SH from Santa Cruz Biotechnology
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hyccin shRNA (h) Lentiviral Particles - sc-89596-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU055301 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8156 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8156 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR13205 from Sigma-Aldrich
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FAM126A siRNA (Human) - CRJ3569 from Cohesion Biosciences
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FAM126A - MBS8207337 from MyBioSource
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shRNA set against Human FAM126A (NM_032581.3) - SHH289445 from Creative biogene
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FAM126A shRNA Plasmid (Human) - CHJ3569 from Cohesion Biosciences
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FAM126A miRNA 3'UTR clone - MiUTR4H-TG03367 from Creative biogene
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