Gene Symbol | CRAT |
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Entrez Gene | 1384 |
Alt Symbol | CAT1 |
Species | Human |
Gene Type | protein-coding |
Description | carnitine O-acetyltransferase |
Other Description | CAT|carnitine acetylase|carnitine acetyltransferase |
Swissprots | Q5T952 Q9BW16 P43155 |
Accessions | EAW87873 EAW87874 EAW87875 P43155 AK313931 AL523652 BC000723 AAH00723 BI460020 BI752361 BQ068230 BT006801 AAP35447 X78706 CAA55359 XM_005251706 XP_005251763 XM_005251708 XP_005251765 NM_000755 NP_000746 NM_001257363 NP_001244292 NM_004003 NM_144782 |
Function | Carnitine acetylase is specific for short chain fatty acids. Carnitine acetylase seems to affect the flux through the pyruvate dehydrogenase complex. It may be involved as well in the transport of acetyl-CoA into mitochondria. |
Subcellular Location | Isoform 2: Peroxisome {ECO:0000305}. |
Tissue Specificity | Mostly in skeletal muscle, less in heart, liver and pancreas, only weakly detectable in brain, placenta, lung and kidney. |
Top Pathways | Peroxisome |
CAT CRISPR/Cas9 KO Plasmid (h) - sc-404860 from Santa Cruz Biotechnology
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CAT HDR Plasmid (h) - sc-404860-HDR from Santa Cruz Biotechnology
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CAT Double Nickase Plasmid (h) - sc-404860-NIC from Santa Cruz Biotechnology
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CAT Double Nickase Plasmid (h2) - sc-404860-NIC-2 from Santa Cruz Biotechnology
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CAT CRISPR Activation Plasmid (h) - sc-404860-ACT from Santa Cruz Biotechnology
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CAT CRISPR Activation Plasmid (h2) - sc-404860-ACT-2 from Santa Cruz Biotechnology
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CAT Lentiviral Activation Particles (h) - sc-404860-LAC from Santa Cruz Biotechnology
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CAT Lentiviral Activation Particles (h2) - sc-404860-LAC-2 from Santa Cruz Biotechnology
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CAT siRNA (h) - sc-41467 from Santa Cruz Biotechnology
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CAT shRNA Plasmid (h) - sc-41467-SH from Santa Cruz Biotechnology
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CAT shRNA (h) Lentiviral Particles - sc-41467-V from Santa Cruz Biotechnology
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CRAT RNAi - H00001384-R01 from Novus Biologicals
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MISSION® esiRNA - EHU088681 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6544 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6544 from Sigma-Aldrich
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CRAT siRNA (Human) - CRH0970 from Cohesion Biosciences
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CRAT RNAi - H00001384-R02 from Novus Biologicals
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CRAT - MBS8215734 from MyBioSource
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shRNA set against Human CRAT (NM_000755.3) - SHH269189 from Creative biogene
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Human CRAT siRNA - orb261472 from Biorbyt
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CRAT shRNA Plasmid (Human) - CHH0970 from Cohesion Biosciences
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CRAT miRNA 3'UTR clone - MiUTR3H-03173 from Creative biogene
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