Gene Symbol |
STOML3
|
Entrez Gene |
161003
|
Alt Symbol |
Epb7.2l, SRO
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
stomatin (EPB72)-like 3
|
Other Description |
SLP-3|erythrocyte band 7 integral membrane protein|protein 7.2B|stomatin-like protein 3
|
Swissprots |
Q5JS35 B4E285 Q8TAV4
|
Accessions |
CAG30025 CAV31089 EAX08609 Q8TAV4 AK304159 BAG65047 AK313632 BAG36391 BC025760 AAH25760 BM982114 DB200356 DQ891676 ABM82602 EU176604 ABW03405 XM_011534946 XP_011533248 XM_011534947 XP_011533249 NM_001144033 NP_001137505 NM_145286 NP_660329
|
Function |
Required for the function of many mechanoreceptors. Modulate mechanotransduction channels and acid-sensing ion channels (ASIC) proteins. Potentiates PIEZO1 and PIEZO2 function by increasing their sensitivity to mechanical stimulations. {ECO:0000250|UniProtKB:Q6PE84}.
|
Subcellular Location |
Cell membrane {ECO:0000250|UniProtKB:Q6PE84}; Single-pass type III membrane protein {ECO:0000250|UniProtKB:Q6PE84}. Note=Detected in lipid rafts. {ECO:0000250|UniProtKB:Q6PE84}.
|